Litchfield J C, Keighley M R, Myatt I W, Edwards M C
Br J Surg. 1979 Mar;66(3):188-90. doi: 10.1002/bjs.1800660315.
A randomized controlled trial has investigated the value of cefuroxime (a new antibiotic resistant to beta-lactamase) in 80 patients with established postoperative respiratory infection. Although the majority of respiratory isolates were sensitive to cefuroxime, there was no significant advantage in the antibiotic group compared with the controls with respect to duration of fever, radiological abnormality or infected sputum. We conclude that antibiotics are rarely necessary for the majority of patients who develop postoperative respiratory infections.
一项随机对照试验研究了头孢呋辛（一种对β-内酰胺酶有抗性的新型抗生素）对80例确诊为术后呼吸道感染患者的疗效。尽管大多数呼吸道分离菌对头孢呋辛敏感，但与对照组相比，抗生素组在发热持续时间、放射学异常或痰液感染方面并无显著优势。我们得出结论，大多数发生术后呼吸道感染的患者很少需要使用抗生素。
