Institute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, China.
Molecules. 2023 Apr 29;28(9):3806. doi: 10.3390/molecules28093806.
Cannabis ( L.) is an ancient cultivated plant that contains less than 0.3% tetrahydrocannabinol (THC). It is widely utilized at home and abroad and is an economic crop with great development and utilization value. There are 31 countries legalizing industrial cannabis cultivation. Cannabis fiber has been used for textile production in China for 6000 years. China is the largest producer and exporter of cannabis. China may still play a leading role in the production of cannabis fiber. China has a long history of cannabis cultivation and rich germplasm resources. Yunnan, Heilongjiang, and Jilin are three Chinese provinces where industrial cannabis can be grown legally. Cannabinoids are terpenoid phenolic compounds produced during the growth, and which development of cannabis and are found in the glandular hairs of female flowers at anthesis. They are the active chemical components in the cannabis plant and the main components of cannabis that exert pharmacological activity. At the same time, research in China on the use of cannabis in the food industry has shown that industrial cannabis oil contains 13-20% oleic acid, 40-60% omega-6 linoleic acid, and 15-30% omega-3 α-linolenic acid. At present, more than 100 cannabinoids have been identified and analyzed in China, among which phenolic compounds are the main research objects. For instance, phenolic substances represented by cannabidiol (CBD) have rich pharmacological effects. There are still relatively little research on cannabinoids, and a comprehensive introduction to research progress in this area is needed. This paper reviews domestic and foreign research progress on cannabinoids in cannabis sativa, which is expected to support cannabis-related research and development.
大麻(L.)是一种古老的栽培植物,其四氢大麻酚(THC)含量低于 0.3%。它在国内外都得到了广泛的应用,是一种具有巨大发展和利用价值的经济作物。目前有 31 个国家批准了工业大麻种植合法化。中国用大麻纤维进行纺织品生产已有 6000 年的历史。中国是大麻的最大生产国和出口国。中国在大麻纤维的生产中可能仍将发挥主导作用。中国大麻种植历史悠久,种质资源丰富。云南、黑龙江和吉林是中国三个可以合法种植工业大麻的省份。大麻素是大麻生长过程中产生的萜类酚类化合物,在花期雌性花的腺毛中发育,并存在于其中。它们是大麻植物中的活性化学成分,也是发挥药理活性的大麻主要成分。同时,中国对大麻在食品工业中应用的研究表明,工业大麻油含有 13-20%的油酸、40-60%的ω-6 亚油酸和 15-30%的ω-3α-亚麻酸。目前,中国已鉴定和分析了 100 多种大麻素,其中酚类化合物是主要的研究对象。例如,以大麻二酚(CBD)为代表的酚类物质具有丰富的药理作用。对大麻素的研究还相对较少,需要对这一领域的研究进展进行全面介绍。本文综述了国内外对大麻中大麻素的研究进展,有望为大麻相关研究和开发提供支持。