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大麻二酚提取物显示出对抗 和 的有前景的抗菌活性。

CBD Extract Shows Promising Antibacterial Activity against and .

机构信息

The Microbiology Program, College of Science, Technology, Engineering, and Mathematics (C-STEM), Alabama State University, Montgomery, AL 36104, USA.

The Biomedical Engineering Program, College of Science, Technology, Engineering, and Mathematics (C-STEM), Alabama State University, Montgomery, AL 36104, USA.

出版信息

Molecules. 2022 Apr 21;27(9):2669. doi: 10.3390/molecules27092669.

Abstract

Products derived from L. have gained increased interest and popularity. As these products become common amongst the public, the health and potential therapeutic values associated with hemp have become a premier focus of research. While the psychoactive and medicinal properties of products have been extensively highlighted in the literature, the antibacterial properties of cannabidiol (CBD) have not been explored in depth. This research serves to examine the antibacterial potential of CBD against and . . In this study, we observed bacterial response to CBD exposure through biological assays, bacterial kinetics, and fluorescence microscopy. Additionally, comparative studies between CBD and ampicillin were conducted against . and . to determine comparative efficacy. Furthermore, we observed potential resistance development of our spp. against CBD treatment.

摘要

从 L. 中提取的产品引起了人们越来越多的兴趣和关注。随着这些产品在公众中变得越来越普遍,与大麻相关的健康和潜在治疗价值已成为研究的重点。虽然 产品的致幻和药用特性在文献中已经得到了广泛的强调,但大麻二酚 (CBD) 的抗菌特性尚未得到深入研究。本研究旨在检查 CBD 对 和 的抗菌潜力。在这项研究中,我们通过生物测定、细菌动力学和荧光显微镜观察了细菌对 CBD 暴露的反应。此外,还对 CBD 和氨苄西林进行了比较研究,以确定其对 和 的相对疗效。此外,我们还观察了我们的 spp. 对 CBD 治疗产生潜在耐药性的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ae8/9099639/a6fe40a29d7d/molecules-27-02669-g001a.jpg

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