Ismail Tevfik F, Frey Simon, Kaufmann Beat A, Winkel David J, Boll Daniel T, Zellweger Michael J, Haaf Philip
King's College London & Cardiology Department, School of Biomedical Engineering and Imaging Sciences, Guy's and St Thomas' NHS Foundation Trust, London SE1 7EH, UK.
Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Petersgraben 4, CH-4031 Basel, Switzerland.
J Clin Med. 2023 Apr 25;12(9):3122. doi: 10.3390/jcm12093122.
Hypertensive heart disease (HHD) develops in response to the chronic exposure of the left ventricle and left atrium to elevated systemic blood pressure. Left ventricular structural changes include hypertrophy and interstitial fibrosis that in turn lead to functional changes including diastolic dysfunction and impaired left atrial and LV mechanical function. Ultimately, these changes can lead to heart failure with a preserved (HFpEF) or reduced (HFrEF) ejection fraction. This review will outline the clinical evaluation of a patient with hypertension and/or suspected HHD, with a particular emphasis on the role and recent advances of multimodality imaging in both diagnosis and differential diagnosis.
高血压性心脏病（HHD）是由于左心室和左心房长期暴露于升高的体循环血压而发生的。左心室结构变化包括肥厚和间质纤维化，进而导致功能变化，包括舒张功能障碍以及左心房和左心室机械功能受损。最终，这些变化可导致射血分数保留（HFpEF）或降低（HFrEF）的心力衰竭。本综述将概述高血压和/或疑似HHD患者的临床评估，特别强调多模态成像在诊断和鉴别诊断中的作用及最新进展。
