CMR Unit, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Cardiology Department, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Eur Heart J Cardiovasc Imaging. 2022 Mar 22;23(4):450-464. doi: 10.1093/ehjci/jeac021.
Inflammatory cardiomyopathy (I-CMP) is defined as myocarditis in association with cardiac dysfunction and/or ventricular remodelling. It is characterized by inflammatory cell infiltration into the myocardium and has heterogeneous infectious and non-infectious aetiologies. A complex interplay of genetic, autoimmune, and environmental factors contributes to the substantial risk of deteriorating cardiac function, acute heart failure, and arrhythmia as well as chronic dilated cardiomyopathy and its sequelae. Multi-parametric cardiovascular magnetic resonance (CMR) imaging is sensitive to many tissue changes that occur during myocardial inflammation, regardless of its aetiology. In this review, we summarize the various aetiologies of I-CMP and illustrate how CMR contributes to non-invasive diagnosis.
炎症性心肌病（I-CMP）定义为伴有心功能障碍和/或心室重构的心肌炎。其特征是炎症细胞浸润心肌，具有异源性感染性和非感染性病因。遗传、自身免疫和环境因素的复杂相互作用导致心脏功能恶化、急性心力衰竭和心律失常以及慢性扩张型心肌病及其后遗症的风险显著增加。多参数心血管磁共振（CMR）成像对心肌炎症过程中发生的许多组织变化敏感，而与病因无关。在这篇综述中，我们总结了 I-CMP 的各种病因，并说明了 CMR 如何有助于非侵入性诊断。
