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[硬化性胆管炎、慢性胰腺炎和干燥综合征]

[Sclerosing cholangitis, chronic pancreatitis and Sjögren's syndrome].

作者信息

Versapuech J M, Labayle D, Grange D, Fischer D, Kemeny F, D'Hubert E

出版信息

Ann Med Interne (Paris). 1986;137(2):147-51.

PMID:3717820
Abstract

A 63 year old man was followed up for chronic pancreatitis. After 2 years, he developed features of primary sclerosing cholangitis associated with Sjögren's syndrome. A review of the literature revealed 38 previous cases of chronic pancreatitis associated with sclerosing cholangitis; a sicca complex was also demonstrated in 3 of these cases. Chronic pancreatitis is mostly asymptomatic and the diagnosis is usually made at laparotomy or postmortem. Retrograde pancreatograms are abnormal in 15-75 p. 100 of patients with primary sclerosing cholangitis. The relationship between the two diseases is not a coincidence. On the other hand, the significance of the association with the Sjögren's syndrome remains controversial.

摘要

一名63岁男性因慢性胰腺炎接受随访。两年后,他出现了与干燥综合征相关的原发性硬化性胆管炎的特征。文献回顾显示,此前有38例慢性胰腺炎合并硬化性胆管炎的病例;其中3例还表现出干燥综合征。慢性胰腺炎大多无症状,诊断通常在剖腹手术时或尸检时做出。在原发性硬化性胆管炎患者中,逆行胰胆管造影有15% - 75%显示异常。这两种疾病之间的关系并非巧合。另一方面,与干燥综合征关联的意义仍存在争议。

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