Imbriani M, Ghittori S, Prestinoni A, Longoni P, Cascone G, Gamba G
Arch Environ Health. 1986 Mar-Apr;41(2):90-3. doi: 10.1080/00039896.1986.9937415.
The effects of dimethylformamide (DMF) on hemostatic functions, especially on platelet activity, were examined both in vitro and in vivo in 15 workers exposed to DMF (27 mg/m3, median value). Twenty-eight control subjects who were not exposed to DMF, but comparable for age, anthropometric data, and smoking habits, were also studied. Workers exposed to DMF showed a decrease in the number of platelets and had longer coagulation times, probably due to a change caused by DMF on the membrane receptor of platelets and on the phospholipid components of the clotting system.
在15名接触二甲基甲酰胺（DMF）（中位数为27毫克/立方米）的工人中，对二甲基甲酰胺（DMF）对止血功能，特别是对血小板活性的影响进行了体内和体外研究。还研究了28名未接触DMF但年龄、人体测量数据和吸烟习惯相当的对照对象。接触DMF的工人血小板数量减少，凝血时间延长，这可能是由于DMF对血小板膜受体和凝血系统磷脂成分的改变所致。
