Basu Manabendra, Sunil H V, Kannan Subramanian
Department of General Medicine, Narayana Hrudayalaya Hospitals, Bengaluru, Karnataka, India.
Department of Nuclear Medicine, Narayana Hrudayalaya Hospitals, Bengaluru, Karnataka, India.
Indian J Nucl Med. 2023 Jan-Mar;38(1):81-83. doi: 10.4103/ijnm.ijnm_93_22. Epub 2023 Feb 24.
Ectopic thyroid tissue can be present in the embryonal path of descent of the thyroglossal duct anywhere from the foramen caecum to the thyroid gland. However, for such ectopic thyroid tissue to be hyperfunctioning is quite rare. Here, we discuss a 56-year-old female patient who presented with persistent thyrotoxicosis for over 7 years. She had undergone thyroidectomy in 1982 for thyrotoxicosis and was rendered hypothyroid (thyroid-stimulating hormone of 75 μIU/mL). Whole-body technetium scan was done twice which did not show any uptake in the neck or other parts of the body and an empirical dose of 15 mCi of radioiodine therapy was also given to treat the thyrotoxicosis. She continued to be thyrotoxic and was on carbimazole 30 mg/day along with beta-blockers. In 2021, an Iodine whole-body scan revealed small remnant thyroid tissue and an ectopic thyroid tissue in a thyroglossal cyst. In such cases of persistent or recurrent thyrotoxicosis despite standard treatments, an ectopic location should be sought after and treated.
异位甲状腺组织可出现在甲状舌管胚胎下降路径上，从盲孔到甲状腺的任何部位。然而，这种异位甲状腺组织出现功能亢进的情况相当罕见。在此，我们讨论一名56岁女性患者，她出现持续性甲状腺毒症超过7年。1982年她因甲状腺毒症接受了甲状腺切除术，术后出现甲状腺功能减退（促甲状腺激素为75 μIU/mL）。进行了两次全身锝扫描，颈部或身体其他部位均未显示任何摄取，还给予了15 mCi的经验性放射性碘治疗剂量来治疗甲状腺毒症。她仍持续甲状腺毒症，每天服用30 mg卡比马唑并联合使用β受体阻滞剂。2021年，碘全身扫描显示甲状舌管囊肿内有小的残余甲状腺组织和一个异位甲状腺组织。在这种尽管经过标准治疗仍持续或复发甲状腺毒症的病例中，应寻找异位部位并进行治疗。
