Ren Rujing, Qi Jinlei, Lin Shaohui, Liu Xinya, Yin Peng, Wang Zhihui, Tang Ran, Wang Jintao, Huang Qiang, Li Jianping, Xie Xinyi, Hu Yongbo, Cui Shishuang, Zhu Yuan, Yu Xiaoping, Wang Pengfei, Zhu Yikang, Wang Yiran, Huang Yanyan, Hu Yisong, Wang Ying, Li Chunbo, Zhou Maigeng, Wang Gang
Department of Neurology and Institute of Neurology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Gen Psychiatr. 2022 Mar 11;35(1):e100751. doi: 10.1136/gpsych-2022-100751. eCollection 2022.
China's population has rapidly aged over the recent decades of social and economic development as neurodegenerative disorders have proliferated, especially Alzheimer's disease (AD) and related dementias (ADRD). AD's incidence rate, morbidity, and mortality have steadily increased to make it presently the fifth leading cause of death among urban and rural residents in China and magnify the resulting financial burdens on individuals, families and society. The 'Healthy China Action' plan of 2019-2030 promotes the transition from disease treatment to health maintenance for this expanding population with ADRD. This report describes related epidemiological trends, evaluates the economic burden of the disease, outlines current clinical diagnosis and treatment status and delineates existing available public health resources. More specifically, it examines the public health impact of ADRD, including prevalence, mortality, costs, usage of care, and the overall effect on caregivers and society. In addition, this special report presents technical guidance and supports for the prevention and treatment of AD, provides expertise to guide relevant governmental healthcare policy development and suggests an information platform for international exchange and cooperation.
在近几十年的社会经济发展过程中，中国人口迅速老龄化，神经退行性疾病激增，尤其是阿尔茨海默病（AD）和相关痴呆症（ADRD）。AD的发病率、患病率和死亡率持续上升，目前已成为中国城乡居民第五大死因，加重了个人、家庭和社会的经济负担。《健康中国行动（2019—2030年）》推动针对这一不断增加的ADRD人群从疾病治疗向健康维护转变。本报告描述了相关流行病学趋势，评估了疾病的经济负担，概述了当前的临床诊断和治疗状况，并阐述了现有的公共卫生资源。更具体地说，它研究了ADRD对公共卫生的影响，包括患病率、死亡率、成本、护理使用情况以及对护理人员和社会的总体影响。此外，本专题报告提供了AD预防和治疗的技术指导与支持，为政府相关医疗政策的制定提供专业知识，并建议建立一个国际交流与合作的信息平台。
