Jiang Miaomiao, Lu Tianlan, Yang Kang, Li Xianjing, Zhao Liyang, Zhang Dai, Li Jun, Wang Lifang
National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), NHC Key Laboratory of Mental Health (Peking University), Peking University Sixth Hospital, Peking University Institute of Mental Health, Beijing, China.
Translational Medicine Center of Chinese Institute for Brain Research, Beijing, China.
Front Psychiatry. 2023 Apr 25;14:1096769. doi: 10.3389/fpsyt.2023.1096769. eCollection 2023.
In recent years, a large number of studies have focused on autism spectrum disorder (ASD). The present study used bibliometric analysis to describe the state of ASD research over the past decade and identify its trends and research fronts.
Studies on ASD published from 2011 to 2022 were obtained from the Web of Science Core Collection (WoSCC). Bibliometrix, CiteSpace, and VOSviewer were used for bibliometric analysis.
A total of 57,108 studies were included in the systematic search, and articles were published in more than 6,000 journals. The number of publications increased by 181.7% (2,623 in 2011 and 7,390 in 2021). The articles in the field of genetics are widely cited in immunology, clinical research, and psychological research. Keywords co-occurrence analysis revealed that "causative mechanisms," "clinical features," and "intervention features" were the three main clusters of ASD research. Over the past decade, genetic variants associated with ASD have gained increasing attention, and immune dysbiosis and gut microbiota are the new development frontiers after 2015.
This study uses a bibliometric approach to visualize and quantitatively describe autism research over the last decade. Neuroscience, genetics, brain imaging studies, and gut microbiome studies improve our understanding of autism. In addition, the microbe-gut-brain axis may be an exciting research direction for ASD in the future. Therefore, through visual analysis of autism literature, this paper shows the development process, research hotspots, and cutting-edge trends in this field to provide theoretical reference for the development of autism in the future.
近年来，大量研究聚焦于自闭症谱系障碍（ASD）。本研究采用文献计量分析方法描述过去十年ASD研究的状况，并确定其趋势和研究前沿。
从科学网核心合集（WoSCC）获取2011年至2022年发表的关于ASD的研究。使用Bibliometrix、CiteSpace和VOSviewer进行文献计量分析。
系统检索共纳入57108项研究，这些文章发表在6000多种期刊上。出版物数量增长了181.7%（2011年为2623篇，2021年为7390篇）。遗传学领域的文章在免疫学、临床研究和心理学研究中被广泛引用。关键词共现分析表明，“致病机制”“临床特征”和“干预特征”是ASD研究的三个主要聚类。在过去十年中，与ASD相关的基因变异受到越来越多的关注，免疫失调和肠道微生物群是2015年后的新发展前沿。
本研究采用文献计量方法对过去十年的自闭症研究进行可视化和定量描述。神经科学、遗传学、脑成像研究和肠道微生物组研究增进了我们对自闭症的理解。此外，微生物-肠道-脑轴可能是未来ASD一个令人兴奋的研究方向。因此，通过对自闭症文献的可视化分析，本文展示了该领域的发展过程、研究热点和前沿趋势，为未来自闭症的发展提供理论参考。
