Clinic of Radiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin University Hospital, Kollárova 2, 036 59, Martin, Slovakia.
Department of Thoracic Surgery, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin University Hospital, Kollárova 2, 036 59, Martin, Slovakia.
Neuro Endocrinol Lett. 2023 Apr 30;44(2):105-114.
The current retrospective study focused on evaluation of the relationship between pulmonary embolism during COVID-19 pandemic and demographic, presenting symptoms, comorbidities and laboratory results in patients who underwent CT angiography of the pulmonary arteries.
The study enrolled all adult patients with suspected acute pulmonary embolism (PE) who underwent computed tomography pulmonary angiography (CTPA) between March 1, 2020, and April 30, 2022, during the SARS-CoV-2 pandemic. 1698 CTPAs were reviewed and various data were collected. Based on examination results, patients were divided into 4 groups: a group with positive PE and a group with negative PE for both COVID-19 and non-COVID-19 patients.
When comparing different predictors of COVID-19 patients and non-COVID-19 patients we noticed lower probability of PE in female gender (OR 0.77, 95% CI: 0.60-1.00, p = 0.052) and in chronic obstructive pulmonary disease (COPD) patients (OR 0.6, 95% CI: 0.38-0.90, p = 0.017). Higher probability of PE was in cases of older age (OR 1.02, 95% CI: 1.01-1.02, p < 0.001), increased heart rate (OR 1.01, 95% CI: 1.01-1.02, p < 0.001) and increased D-dimer levels (OR 1.03, 95% CI: 1.02-1.04, p < 0.001).
Considering predictors of PE there was a significantly lower risk of PE in the female gender and COPD, and a higher risk with increasing age, heart rate, and D-dimer levels.
本回顾性研究旨在评估 COVID-19 大流行期间肺栓塞与行肺动脉 CT 血管造影（CTPA）的患者的人口统计学、临床表现、合并症和实验室结果之间的关系。
该研究纳入了 2020 年 3 月 1 日至 2022 年 4 月 30 日期间因疑似急性肺栓塞（PE）而行 CTPA 的所有成年患者。回顾了 1698 例 CTPA，并收集了各种数据。根据检查结果，患者分为 4 组：COVID-19 阳性和 COVID-19 阴性的 PE 阳性组和 PE 阴性组。
在比较 COVID-19 患者和非 COVID-19 患者的不同预测因素时，我们注意到女性（OR 0.77，95%CI：0.60-1.00，p=0.052）和慢性阻塞性肺疾病（COPD）（OR 0.6，95%CI：0.38-0.90，p=0.017）患者发生 PE 的可能性较低。年龄较大（OR 1.02，95%CI：1.01-1.02，p<0.001）、心率加快（OR 1.01，95%CI：1.01-1.02，p<0.001）和 D-二聚体水平升高（OR 1.03，95%CI：1.02-1.04，p<0.001）的患者发生 PE 的可能性更高。
考虑到 PE 的预测因素，女性和 COPD 患者发生 PE 的风险显著降低，而年龄、心率和 D-二聚体水平升高的患者发生 PE 的风险增加。
