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免疫功能正常个体手部的罕见、非典型感染。

Rare, Atypical Infection of the Hand in Immunocompetent Individuals.

作者信息

Burns Jersey, Chao Linda, Palavecino Elizabeth, Qasem Shadi, Li Zhongyu

机构信息

Department of Orthopaedic Surgery Atrium Health Wake Forest Baptist Medical Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina.

Department of Pathology, Atrium Health Wake Forest Baptist Medical Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina.

出版信息

J Surg Orthop Adv. 2023 Spring;32(1):55-58.

PMID:37185079
Abstract

We present two cases of immunocompetent individuals diagnosed with nontuberculous infections of the hand caused by organisms rarely seen in the clinical setting: Mycobacterium heckeshornense and Mycobacterium chelonae. In the first case, a 50-year-old male presented with tenosynovitis of left long finger. He was subsequently found to have a Mycobacterium heckeshornense infection that was resolved with multiple surgeries and a long-term regimen of several antibiotics. The second case was a 29-year-old female with a history of a trivial hand injury infected with Mycobacterium chelonae. She was successfully treated with surgical debridement and antibiotics over the course of eight months. It is important to recognize the increasing prevalence of these two species of bacteria as human pathogens that can result in infections of the extremities even in immunocompetent individuals. (Journal of Surgical Orthopaedic Advances 32(1):055-058, 2023).

摘要

我们报告了两例免疫功能正常的个体,他们被诊断出手部患有非结核性感染,病原体在临床环境中很少见:赫克霍恩分枝杆菌和龟分枝杆菌。第一例中,一名50岁男性出现左手中指腱鞘炎。随后发现他感染了赫克霍恩分枝杆菌,通过多次手术和长期使用多种抗生素的方案得以治愈。第二例是一名29岁女性,有手部轻微受伤史,感染了龟分枝杆菌。她在八个月的时间里通过手术清创和抗生素治疗成功治愈。认识到这两种细菌作为人类病原体的患病率不断上升很重要,它们即使在免疫功能正常的个体中也可能导致肢体感染。(《外科骨科进展杂志》32(1):055 - 058, 2023)

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