Newton J A, Camplejohn R S, McGibbon D H
Br J Dermatol. 1986 Jun;114(6):691-4. doi: 10.1111/j.1365-2133.1986.tb04877.x.
Distinct aneuploid clones of keratinocytes were detected in six cases of cutaneous Bowen's disease. As Bowen's disease is an accepted precursor of malignancy, aneuploidy may prove to be a useful indicator of the risk of invasive change in dermatoses questionably pre-malignant.
