新型冠状病毒肺炎机械通气后的气道后遗症：一项范围综述方案

Airway Sequelae After Mechanical Ventilation for COVID-19: Protocol for a Scoping Review.

作者信息

Candelo Estephania, Arias-Valderrama Oriana, Triviño-Arias Jacobo, Quiroz Felipe, Isaza-Pierotti Daniel Francisco, Victoria William, Tintinago Luis F

机构信息

Head and Neck Department, Fundacion Valle del Lili, Cali, Colombia.

Centro de Investigaciones Clinicas, Fundacion Valle del Lili, Cali, Colombia.

出版信息

JMIR Res Protoc. 2023 Nov 29;12:e41811. doi: 10.2196/41811.

DOI:10.2196/41811

PMID:37191952

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10719820/

Abstract

BACKGROUND

The epidemiology, morbidity, and burden of disease related to airway sequelae associated with invasive mechanical ventilation in the context of the COVID-19 pandemic remain unclear.

OBJECTIVE

This scoping review aims to summarize the current knowledge regarding airway sequelae after severe SARS-CoV-2 infection. This knowledge will help guide research endeavors and decision-making in clinical practice.

METHODS

This scoping review will include participants of all genders, and no particular age group who developed post-COVID-19 airway-related complication will be excluded. No exclusion criteria will be applied from country, language, or document type. The information source will include analytical observational studies. Unpublished data will not be completely covered as gray literature will be covered. A total of 2 independent reviewers will participate in the process of screening, selection, and data extraction, and the whole process will be performed blindly. Conflict between the reviewers will be solved through discussion and an additional reviewer. The results will be reported by using descriptive statistics, and information will be displayed on RedCap (Research Electronic Data Capture).

RESULTS

The literature search was conducted in May 2022 in the following databases: PubMed, Embase, SCOPUS, Cochrane Library, as well as LILACS and gray literature to identify observational studies; a total of 738 results were retrieved. The scoping review will be finished by March 2023.

CONCLUSIONS

This scoping review will describe current knowledge on the most frequently encountered laryngeal or tracheal sequelae in patients exposed to mechanical ventilation due to SARS-CoV-2 infection. This scoping review will find the incidence of airway sequelae post COVID-19 and the most common sequelae such as airway granuloma, vocal fold paralysis, and airway stenoses. Future studies should evaluate the incidence of these disorders.

INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/41811.

摘要

背景

在新冠疫情背景下，与有创机械通气相关的气道后遗症的流行病学、发病率和疾病负担仍不明确。

目的

本范围综述旨在总结关于严重感染SARS-CoV-2后气道后遗症的现有知识。这些知识将有助于指导临床实践中的研究工作和决策。

方法

本范围综述将纳入所有性别的参与者，不排除任何特定年龄组且患有新冠后气道相关并发症的患者。不适用来自国家、语言或文献类型的排除标准。信息来源将包括分析性观察性研究。由于将涵盖灰色文献，未发表的数据将不会被完全覆盖。共有2名独立评审员将参与筛选、选择和数据提取过程，且整个过程将在盲态下进行。评审员之间的冲突将通过讨论和额外的评审员来解决。结果将采用描述性统计报告，并在RedCap（研究电子数据采集）上展示信息。