Nakada T, Kwee I L
Brain. 1986 Jun;109 ( Pt 3):431-41. doi: 10.1093/brain/109.3.431.
Five cases of oculopalatal myoclonus (OPM) were studied. Three exhibited the lateral form, characterized by jerky nystagmoid eye movements with simultaneous oblique and rotatory components, associated with lateralized palatal myoclonus, and 2 the midline form, characterized by vertical to-and-fro pendular eye movements with symmetric bilateral palatal myoclonus. Structural studies using computed tomography (CT) and proton nuclear magnetic resonance (NMR) imaging indicated that the integrity of the flocculus was preserved in all 5 cases. We postulate that the generation of ocular oscillations in OPM involves vestibulo-ocular reflex (VOR) adaptation mediated by the flocculus. The lateral form represents unilateral disease, whereas the midline form represents bilateral disease.
对5例眼腭肌阵挛（OPM）患者进行了研究。其中3例表现为外侧型，其特征为眼球呈急跳性眼球震颤样运动，同时伴有斜向和旋转成分，伴有单侧腭肌阵挛；2例为中线型，其特征为眼球垂直往返摆动，伴有双侧对称腭肌阵挛。使用计算机断层扫描（CT）和质子核磁共振（NMR）成像进行的结构研究表明，所有5例患者的小脑绒球完整性均得以保留。我们推测，OPM中眼球震颤的产生涉及由绒球介导的前庭眼反射（VOR）适应。外侧型代表单侧疾病，而中线型代表双侧疾病。
