Madden Kenneth M, Feldman Boris, Chase Jocelyn
Gerontology and Diabetes Research Laboratory, Division of Geriatric Medicine, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Centre for Hip Health and Mobility, University of British Columbia, Vancouver, British Columbia, Canada.
Sleep Adv. 2022 Nov 23;3(1):zpac042. doi: 10.1093/sleepadvances/zpac042. eCollection 2022.
Sleep disruption is a risk factor for obesity, diabetes, and cardiovascular disease in older adults. How physical activity (PA) interacts with the negative cardiometabolic effects of poor sleep is not known. We objectively measured sleep efficiency (SE) in very active older adults and examined the association between SE and a continuous Metabolic Syndrome Risk Score (cMSy).
Very active older adults (age ≥65 years) from a Master's Ski Team (Whistler, Canada) were recruited. Each participants wore an activity monitor (SenseWear Pro) continuously for 7 days to provide measures of both daily energy expenditure (metabolic equivalents, METs) and SE. All components of the metabolic syndrome were measured and a principal component analysis was used to compute a continuous metabolic risk score (cMSy, sum of eigenvalues ≥1.0).
A total of 54 participants (mean age 71.4 years, SD 4.4 years, and 24 men and 30 women) were recruited and had very high PA levels (>2.5 h per day of exercise). Initially, there was no significant association between SE and cMSy ( = 0.222). When stratified by biological sex, only men showed a significant negative association between SE and cMSy (Standardized = -0.364 ± 0.159, = 0.032).
Only older men show a significant negative association between poor SE and increased cardiometabolic risk, despite high levels of PA.
睡眠中断是老年人肥胖、糖尿病和心血管疾病的一个风险因素。身体活动（PA）如何与睡眠不佳的负面心脏代谢效应相互作用尚不清楚。我们客观测量了非常活跃的老年人的睡眠效率（SE），并研究了SE与连续代谢综合征风险评分（cMSy）之间的关联。
招募了来自加拿大惠斯勒一个硕士滑雪队的非常活跃的老年人（年龄≥65岁）。每位参与者连续7天佩戴活动监测器（SenseWear Pro），以提供每日能量消耗（代谢当量，METs）和SE的测量值。测量了代谢综合征的所有组成部分，并使用主成分分析来计算连续代谢风险评分（cMSy，特征值总和≥1.0）。
共招募了54名参与者（平均年龄71.4岁，标准差4.4岁，24名男性和30名女性），他们的PA水平非常高（每天锻炼>2.5小时）。最初，SE与cMSy之间无显著关联（=0.222）。按生物学性别分层时，只有男性的SE与cMSy之间存在显著负相关（标准化=-0.364±0.159，=0.032）。
尽管PA水平很高，但只有老年男性的SE不佳与心脏代谢风险增加之间存在显著负相关。
