Ross C P, Persaud T V
Can J Cardiol. 1986 May-Jun;2(3):160-3.
The influence of alcohol and caffeine on cardiac embryogenesis was investigated in the rat. No disturbances were detected in the yolk sac circulatory system and allantois of embryos exposed to ethanol, but in several cases the cardiac tube was delayed in its development. Caffeine had no gross morphological effect on the developing cardiovascular system. However, cardiac morphogenesis was significantly impaired in embryos recovered from mothers treated with both ethanol and caffeine.
在大鼠中研究了酒精和咖啡因对心脏胚胎发育的影响。在暴露于乙醇的胚胎的卵黄囊循环系统和尿囊中未检测到干扰，但在一些情况下，心管发育延迟。咖啡因对发育中的心血管系统没有明显的形态学影响。然而，从同时接受乙醇和咖啡因治疗的母亲体内回收的胚胎，其心脏形态发生受到显著损害。
