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良性角化病:一个有用的术语?

Benign Keratosis: A Useful Term?

作者信息

Scott Rebecca, Oakley Amanda

机构信息

University of Aberdeen, Waikato Hospital, Hamilton, New Zealand.

Waikato District Health Board, Hamilton, New Zealand.

出版信息

Dermatol Pract Concept. 2023 Apr 1;13(2). doi: 10.5826/dpc.1302a115.

DOI:10.5826/dpc.1302a115
PMID:37196289
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10188172/
Abstract

INTRODUCTION

Seborrheic keratosis (SK), lichen planus-like keratosis (LPLK), and solar lentigo (SL) are common benign skin lesions. These lesions are frequently seen adjacent to each other or can arise from one another. They can sometimes be difficult to differentiate despite having distinct histopathological features.

OBJECTIVES

We evaluated dermoscopic images of 80 skin lesions to confirm the term 'benign keratosis' is useful for an undifferentiated SK/LPLK/SL where there are overlapping clinical and dermoscopic characteristics.

METHODS

Clinical and dermoscopic images were sourced from a teledermoscopy service database of 13,000 lesions in 7,000 patients. The database was queried for SK, SL or LPLK in sun-exposed sites. Each lesion was evaluated based on specific dermoscopic criteria and the results analyzed.

RESULTS

Lesions were identified with mixed clinical and dermoscopic criteria of SK and SL, and in some, dermoscopic criteria for LPLK were also present.

CONCLUSIONS

This study highlights the relationship between these lesions. We confirm the term 'benign keratosis' is useful for mixed lesions or for those that are difficult to classify.

摘要

引言

脂溢性角化病(SK)、扁平苔藓样角化病(LPLK)和日光性雀斑样痣(SL)是常见的良性皮肤病变。这些病变经常彼此相邻出现,或者可能由一种病变发展为另一种。尽管它们具有不同的组织病理学特征,但有时仍难以区分。

目的

我们评估了80例皮肤病变的皮肤镜图像,以确认“良性角化病”这一术语对于具有重叠临床和皮肤镜特征的未分化SK/LPLK/SL是否有用。

方法

临床和皮肤镜图像来自一个远程皮肤镜服务数据库,该数据库包含7000名患者的13000个病变。在该数据库中查询暴露于阳光下部位的SK、SL或LPLK。根据特定的皮肤镜标准对每个病变进行评估,并对结果进行分析。

结果

通过SK和SL的混合临床和皮肤镜标准识别出病变,并且在一些病变中还存在LPLK的皮肤镜标准。

结论

本研究突出了这些病变之间的关系。我们确认“良性角化病”这一术语对于混合性病变或难以分类的病变是有用的。

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本文引用的文献

1
Lichen planus-like keratosis: clinicopathological evaluation of 1366 cases.苔藓样角化病:1366 例的临床病理评估。
Int J Dermatol. 2019 Jul;58(7):830-833. doi: 10.1111/ijd.14358. Epub 2018 Dec 18.
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Clinical and dermoscopic features associated with lichen planus-like keratoses that undergo skin biopsy: A single-center, observational study.临床和皮肤镜特征与接受皮肤活检的扁平苔藓样角化病相关:一项单中心、观察性研究。
Australas J Dermatol. 2019 May;60(2):e119-e126. doi: 10.1111/ajd.12955. Epub 2018 Nov 18.
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Lichen planus-like keratosis: clinical applicability of in vivo reflectance confocal microscopy for an indeterminate cutaneous lesion.扁平苔藓样角化病:体内反射式共聚焦显微镜对不确定皮肤病变的临床适用性
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Chronology of lichen planus-like keratosis features by dermoscopy: a summary of 17 cases.皮肤镜下扁平苔藓样角化病特征的时间顺序:17例总结
Dermatol Pract Concept. 2016 Apr 30;6(2):29-35. doi: 10.5826/dpc.0602a06. eCollection 2016 Apr.
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Better, sooner, more convenient: a successful teledermoscopy service.更好、更快、更便捷:成功的远程皮肤镜服务。
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Seborrheic keratosis.脂溢性角化病。
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Dermoscopy of lichen planus-like keratosis: a model of inflammatory regression.扁平苔藓样角化病的皮肤镜检查:炎症消退模型
J Eur Acad Dermatol Venereol. 2007 Nov;21(10):1392-7. doi: 10.1111/j.1468-3083.2007.02296.x.
8
Dermoscopic pattern of intermediate stage in seborrhoeic keratosis regressing to lichenoid keratosis: report of 24 cases.脂溢性角化病向苔藓样角化病消退的中期皮肤镜表现:24例报告
Br J Dermatol. 2007 Aug;157(2):266-72. doi: 10.1111/j.1365-2133.2007.07963.x. Epub 2007 Jun 6.
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Treatment of solar lentigines.日光性雀斑样痣的治疗。
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Lichen planus-like keratosis. A clinical and histological reexamination.扁平苔藓样角化病。临床与组织学复查。
Am J Surg Pathol. 1993 Mar;17(3):259-63. doi: 10.1097/00000478-199303000-00006.