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一名老年女性的原发性乳腺血管肉瘤:病例报告及文献综述

Primary angiosarcoma of breast in an octogenarian woman: A case report with literature review.

作者信息

Vohra Lubna M, Jabeen Dua, Idrees Romana

机构信息

Department of Breast Surgery, Aga Khan University Hospital, Karachi, Pakistan.

Department of Medical Oncology, Aga Khan University Hospital, Karachi, Pakistan.

出版信息

Int J Surg Case Rep. 2023 Jun;107:108163. doi: 10.1016/j.ijscr.2023.108163. Epub 2023 Apr 11.

Abstract

INTRODUCTION AND IMPORTANCE

Primary breast angiosarcomas are endothelial derived breast sarcomas found in younger to middle age groups. The diagnosis of primary breast angiosarcoma in an octogenarian woman is a rare incidence.

CASE PRESENTATION

We report a case of 87-year-old postmenopausal woman presenting with history of lump in her right breast for four months. Ultrasound guided biopsy was performed which confirmed the diagnosis of angiosarcoma hence, subjected to simple mastectomy. She was doing quite well for one year when ultimately, she developed metastatic disease and couldn't survive more.

CLINICAL DISCUSSION

Microscopically, these tumours are classified into grades I, II and III. Hematogenous route has been taken for metastasis having lungs being most involved. There are limited case reports and studies that have investigated the use of adjuvant radio/chemotherapy.

CONCLUSION

Primary angiosarcoma of breast is a rare disease in old age group with limited treatment options which resulted in poor prognosis and early relapse.

摘要

引言与重要性

原发性乳腺血管肉瘤是一种起源于内皮细胞的乳腺肉瘤,多见于年轻至中年人群。在一位八旬女性中诊断出原发性乳腺血管肉瘤是罕见的病例。

病例报告

我们报告一例87岁绝经后女性,有右乳肿块4个月的病史。进行了超声引导下活检,确诊为血管肉瘤,随后接受了单纯乳房切除术。她术后一年情况良好,但最终出现了转移性疾病,未能存活更长时间。

临床讨论

在显微镜下,这些肿瘤分为I级、II级和III级。转移途径为血行转移,最常累及肺部。关于辅助放疗/化疗应用的病例报告和研究有限。

结论

老年组原发性乳腺血管肉瘤是一种罕见疾病,治疗选择有限,导致预后不良和早期复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f2a/10205444/0a5f7f655ae5/gr1.jpg

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