Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Hunnewell Ground, Boston, MA 02115, USA.
Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 401 Park Drive, Suite 401E, Boston, MA 02215, USA.
Gastroenterol Clin North Am. 2023 Jun;52(2):333-345. doi: 10.1016/j.gtc.2023.02.001. Epub 2023 Apr 7.
Obesity is prevalent and continuing to rise across all age groups, even children. As obesity is challenging to manage and treat, prevention is critical. Here, we highlight nutritional influences during periods of early developmental plasticity, namely the prenatal period and infancy, that have been shown to contribute to the development of obesity into childhood and beyond. We review recent research that examines maternal nutritional factors including dietary patterns and quality, as well as the infant diet, such as complementary foods and beverages, that influence long-term obesity risk. We end with recommendations for clinicians.
肥胖在所有年龄段都很普遍，而且还在不断上升，甚至包括儿童。由于肥胖症难以管理和治疗，因此预防至关重要。在这里，我们重点介绍了在早期发育可塑性期间（即胎儿期和婴儿期）的营养影响，这些影响已被证明有助于肥胖症发展为儿童期及以后。我们回顾了最近的研究，该研究检查了影响长期肥胖风险的母体营养因素，包括饮食模式和质量，以及婴儿饮食，例如补充食品和饮料。最后，我们为临床医生提出了建议。
