Kitsios Katerina, Sharifi Shahriar, Mahmoudi Morteza
Department of Radiology and Precision Health Program, Michigan State University, East Lansing, Michigan 48824, United States.
ACS Pharmacol Transl Sci. 2023 Apr 21;6(5):671-682. doi: 10.1021/acsptsci.3c00044. eCollection 2023 May 12.
Breast cancer is one of the most common cancers in women worldwide, yet conventional treatments have several shortcomings, including low specificity, systemic toxicity, and drug resistance. Nanomedicine technologies provide a promising alternative while also overcoming the limitations posed by conventional therapies. This mini-Review highlights important signaling pathways related to occurrence and development of breast cancer and current breast cancer therapies, followed by an analysis of various nanomedicine technologies developed for diagnosis and treatment of breast cancers.
乳腺癌是全球女性中最常见的癌症之一,然而传统治疗方法存在一些缺点,包括特异性低、全身毒性和耐药性。纳米医学技术提供了一种有前景的替代方案,同时也克服了传统疗法带来的局限性。本综述重点介绍了与乳腺癌发生发展相关的重要信号通路以及当前的乳腺癌治疗方法,随后分析了为乳腺癌诊断和治疗而开发的各种纳米医学技术。