超声引导下经胸肺结节性淀粉样变性的粗针穿刺活检

Ultrasound-controlled transthoracic true-cut needle biopsy in pulmonary nodular amyloidosis.

作者信息

Mihalova Teodora Z, Ivanova Silviya S, Mekov Evgeni V, Yamakova Yordanka Т, Petkov Rosen E

机构信息

Clinic for Treatment of Nonspecific Lung Diseases and Tuberculosis UMHAT "St. Ivan Rilski", Medical University-Sofia Sofia Bulgaria.

Department of Pathomorphology UMHAT "St. Ivan Rilski", Medical University-Sofia Sofia Bulgaria.

出版信息

Respirol Case Rep. 2023 May 16;11(6):e01142. doi: 10.1002/rcr2.1142. eCollection 2023 Jun.

DOI:10.1002/rcr2.1142

PMID:37200954

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10186149/

Abstract

The current case report presents a 59-year-old man with imaging studies of the thorax showing nodular lesions in the lungs bilaterally. Based on radiographic and CT images, preliminary diagnoses for possible granulomatosis (tuberculosis) or pulmonary metastatic dissemination of a neoplastic process were made. An ultrasound-controlled transthoracic true-cut needle biopsy of a subpleural lesion was performed. Special staining with Congo red and examination with a polarizing light microscope for detection of amyloid confirmed the diagnosis of 'pulmonary nodular amyloidosis' by visualizing green birefringence.

摘要

本病例报告介绍了一名59岁男性，其胸部影像学检查显示双侧肺部有结节性病变。根据X线和CT图像，初步诊断可能为肉芽肿病（结核病）或肿瘤性病变的肺转移扩散。对一个胸膜下病变进行了超声引导下经胸真切割针活检。用刚果红进行特殊染色，并使用偏光显微镜检查以检测淀粉样蛋白，通过观察绿色双折射确诊为“肺结节性淀粉样变性”。