Saha Priyanshu, Ajayi Bisola, Minhas Pawan, Lui Darren F
Department of Medicine, St. George's University of London, London, UK.
Department of Complex Neurosurgery, Atkinson Morley Wing, St. George's NHS Foundation Trust, London, UK.
J Surg Case Rep. 2023 May 13;2023(5):rjad244. doi: 10.1093/jscr/rjad244. eCollection 2023 May.
The treatment of spinal cancers has rapidly evolved in the past decade. Often the treatment for spinal metastases required highly morbid surgeries and with palliative outcomes. However, a paradigm shift in surgical oncology has allowed spinal metastases treatment to have curative results. In the state of oligometastatic disease (OMD), the accompaniment of Stereotactic Body Radiotherapy (SBRT) as a primary modality or adjuvant treatment to surgery has been shown to excellent survival outcomes, lower morbidities and better pain management. This case report illustrates a novel approach to the treatment of spinal OMD utilizing anterior spinal separation surgery with a custom carbon fibre vertebral body replacement cage followed by postoperative SBRT with excellent radio-oncological outcomes over 30-month follow-up.
在过去十年中,脊柱癌的治疗方法迅速发展。过去,脊柱转移瘤的治疗通常需要进行高致残性手术,且治疗效果多为姑息性。然而,外科肿瘤学的范式转变使得脊柱转移瘤的治疗能够取得治愈性效果。在寡转移疾病(OMD)状态下,立体定向体部放疗(SBRT)作为主要治疗方式或手术辅助治疗,已被证明能带来出色的生存结果、更低的发病率以及更好的疼痛管理。本病例报告展示了一种治疗脊柱OMD的新方法,即采用前路脊柱分离手术并植入定制碳纤维椎体置换笼,术后进行SBRT,在30个月的随访中取得了出色的放射肿瘤学效果。