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前路脊柱分离手术以实现立体定向体部放疗:一种允许对寡转移疾病进行根治性肿瘤治疗的新方法。

Anterior spinal separation surgery to allow for stereotactic body radiotherapy: a novel approach permitting radical oncological treatment of oligometastatic disease.

作者信息

Saha Priyanshu, Ajayi Bisola, Minhas Pawan, Lui Darren F

机构信息

Department of Medicine, St. George's University of London, London, UK.

Department of Complex Neurosurgery, Atkinson Morley Wing, St. George's NHS Foundation Trust, London, UK.

出版信息

J Surg Case Rep. 2023 May 13;2023(5):rjad244. doi: 10.1093/jscr/rjad244. eCollection 2023 May.

Abstract

The treatment of spinal cancers has rapidly evolved in the past decade. Often the treatment for spinal metastases required highly morbid surgeries and with palliative outcomes. However, a paradigm shift in surgical oncology has allowed spinal metastases treatment to have curative results. In the state of oligometastatic disease (OMD), the accompaniment of Stereotactic Body Radiotherapy (SBRT) as a primary modality or adjuvant treatment to surgery has been shown to excellent survival outcomes, lower morbidities and better pain management. This case report illustrates a novel approach to the treatment of spinal OMD utilizing anterior spinal separation surgery with a custom carbon fibre vertebral body replacement cage followed by postoperative SBRT with excellent radio-oncological outcomes over 30-month follow-up.

摘要

在过去十年中,脊柱癌的治疗方法迅速发展。过去,脊柱转移瘤的治疗通常需要进行高致残性手术,且治疗效果多为姑息性。然而,外科肿瘤学的范式转变使得脊柱转移瘤的治疗能够取得治愈性效果。在寡转移疾病(OMD)状态下,立体定向体部放疗(SBRT)作为主要治疗方式或手术辅助治疗,已被证明能带来出色的生存结果、更低的发病率以及更好的疼痛管理。本病例报告展示了一种治疗脊柱OMD的新方法,即采用前路脊柱分离手术并植入定制碳纤维椎体置换笼,术后进行SBRT,在30个月的随访中取得了出色的放射肿瘤学效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d62/10187476/a5d29f8c7400/rjad244f1.jpg

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