Singer C R, Walker J J, Cameron A, Fraser C
Clin Lab Haematol. 1986;8(1):27-32. doi: 10.1111/j.1365-2257.1986.tb00072.x.
The platelet count does not appear to change during normal pregnancy but a rise in the mean platelet volume (MPV) and platelet distribution width was found in the third trimester in this study of 208 healthy pregnant women. Alteration of all three platelet parameters was seen following delivery in 40 women studied sequentially. Moderately severe pregnancy-induced hypertension (PIH) was associated with no alteration of platelet parameters when compared with gestation-matched controls. Platelet abnormalities in severe PIH appeared to be related to the time of presentation and may be a reflection of the rate of progression of the underlying condition.
在正常妊娠期间血小板计数似乎没有变化,但在这项对208名健康孕妇的研究中发现,孕晚期平均血小板体积(MPV)和血小板分布宽度有所增加。在对40名女性进行连续研究时发现,产后所有三项血小板参数均有改变。与孕周匹配的对照组相比,中度严重的妊娠高血压综合征(PIH)与血小板参数无改变有关。重度PIH中的血小板异常似乎与就诊时间有关,可能反映了潜在病情的进展速度。