School of Medical Sciences, Faculty of Medicine and Health University of Sydney, Westmead Hospital, Westmead, NSW, Australia.
School of Dentistry and Medical Sciences, Faculty of Science and Health, Charles Sturt University, Wagga, Wagga, NSW, Australia.
Methods Mol Biol. 2023;2663:3-38. doi: 10.1007/978-1-0716-3175-1_1.
Hemostasis is a complex but balanced process that permit normal blood flow, without adverse events. Disruption of the balance may lead to bleeding or thrombotic events, and clinical interventions may be required. Hemostasis laboratories typically offer an array of tests, including routine coagulation and specialized hemostasis assays used to guide clinicians for diagnosing and managing patients. Routine assays may be used to screen patients for hemostasis-related disturbances but may also be used for drug monitoring, measuring efficacy of replacement or adjunctive therapy, and other indications, which may then be used to guide further patient management. Similarly, "specialized" assays are used for diagnostic purposes or may be used to monitor or measure efficacy of a given therapy. This chapter provides an overview of hemostasis and thrombosis, with a focus on laboratory testing that may be used to diagnose and help manage patients suspected of hemostasis- and thrombosis-related disorders.
止血是一个复杂但平衡的过程，允许正常的血流而不会产生不良事件。平衡的破坏可能导致出血或血栓形成事件，可能需要临床干预。止血实验室通常提供一系列测试，包括常规凝血和专门的止血测定，用于指导临床医生诊断和治疗患者。常规测定可用于筛查患者的止血相关障碍，也可用于药物监测、评估替代或辅助治疗的效果以及其他适应证，然后可用于指导进一步的患者管理。同样，“专门”的测定用于诊断目的，或用于监测或评估特定治疗的效果。本章概述了止血和血栓形成，重点介绍了可能用于诊断和帮助管理疑似止血和血栓形成相关疾病患者的实验室检测。
