Hemostasis & Thrombosis Center, University of California, Davis Health System, Sacramento, CA, USA.
Methods Mol Biol. 2023;2663:39-50. doi: 10.1007/978-1-0716-3175-1_2.
Hemostasis testing performed in clinical laboratories are critical for assessing hemorrhagic and thrombotic disorders. The assays performed can be used to provide the information required for diagnosis, risk assessment, efficacy of therapy, and therapeutic monitoring. As such, hemostasis tests should be performed to the highest level of quality, including the standardization, implementation, and monitoring of all phases of the testing, which include the preanalytical, analytical, and post-analytical phases. It is well established that the preanalytical phase is the most critical component of the testing process, being the hands-on activities, including patient preparation for blood collection, as well as the actual blood collection, including sample identification and the post-collection handling to include sample transportation, processing, and storage of samples when testing is not performed immediately. The purpose of this article is to provide an update to the previous edition of coagulation testing-related preanalytical variables (PAV) and, when properly addressed and performed, can reduce the most common causes of errors in the hemostasis laboratory.
临床实验室进行的止血检测对于评估出血和血栓形成障碍至关重要。所进行的检测可用于提供诊断、风险评估、治疗效果和治疗监测所需的信息。因此，止血检测应达到最高质量水平，包括检测所有阶段（包括分析前、分析中和分析后阶段）的标准化、实施和监测。已充分证实，分析前阶段是检测过程中最关键的组成部分，涉及到实操活动，包括患者采血前的准备，以及实际采血，包括样本标识和采集后的处理，包括样本运输、处理和储存，当不能立即进行检测时。本文的目的是提供凝血检测相关分析前变量（PAV）的上一版本更新，并在正确处理和执行时，可以减少止血实验室中最常见的错误原因。
