Bilynskiĭ B T, Volod'ko N A
Eksp Onkol. 1986;8(3):47-9.
Comparative investigation of subpopulations and functional properties of lymphocytes isolated from the tumour tissue (TTL) as well as of lymphocytes of the peripheral blood (PBL) of 11 lung cancer patients and 18 breast cancer patients has shown that an increase in the quantity of theophylline-sensitive cells (suppressors and killers) is characteristic of TTL. After 20 hours of incubation of the mixture of the studied lymphocytes and sheep erythrocytes at 4 degrees C an increase in the number of E-RFC proved to be more intensive for TTL than for PBL. The result obtained may suggest the blocking of the superficial receptors of TTL to sheep erythrocytes.
对11名肺癌患者和18名乳腺癌患者的肿瘤组织淋巴细胞(TTL)以及外周血淋巴细胞(PBL)的亚群和功能特性进行的比较研究表明,茶碱敏感细胞(抑制细胞和杀伤细胞)数量增加是TTL的特征。在4℃下将研究的淋巴细胞与绵羊红细胞混合物孵育20小时后,TTL的E-RFC数量增加比PBL更为强烈。所获得的结果可能提示TTL对绵羊红细胞表面受体的阻断作用。