Thangaraj Priyanka, Varadharajan Ramesh
Department of Otorhinolaryngology, Aarupadai Veedu Medical College, Vinayaka Missions Research Foundation, Puducherry, India.
Indian J Otolaryngol Head Neck Surg. 2023 Apr;75(Suppl 1):1078-1083. doi: 10.1007/s12070-023-03622-7. Epub 2023 Mar 2.
Olfactory loss can impair the ability to detect harmful warning smells like smoke or gas leaks, significantly affect the quality of life and increase the morbidity. This study was done using Sniffin stick test kit with an objective to compare the effect of Steroid Nasal Spray with Normal Saline Nasal Spray in improving the olfactory dysfunction seen in cases of chronic nasal obstruction. This Prospective comparative study was conducted on patients presenting to the ENT OPD with olfactory dysfunction due to various nasal pathologies. The olfaction was assessed qualitatively using ODOFIN Sniffin' sticks before and 2 weeks after the use of either a steroid [Group A] or Saline Nasal Spray [Group B] and the results documented and analysed. Total 162 eligible patients were selected. Majority of the study participants were males and the major symptom was Hyposmia. In group A, the initial Sniffin stick test showed Anosmia in 26 and Hyposmia in 55 patients and after 2 weeks, only 2 and 26 patients had Anosmia and Hyposmia respectively. Wherein group B, there was no significant improvement in the olfaction even after 2 weeks of treatment. The improvement in the olfaction was significant between the groups. ( = < 0.001). Our study using ODOFIN Sniffin' sticks for assessing olfactory dysfunction in various nasal pathologies showed that Steroid Nasal Spray is an effective and safe treatment option in managing olfactory dysfunction.
嗅觉丧失会损害检测烟雾或煤气泄漏等有害警示气味的能力,严重影响生活质量并增加发病率。本研究使用嗅觉棒测试套件,目的是比较类固醇鼻喷雾剂与生理盐水鼻喷雾剂对改善慢性鼻阻塞患者嗅觉功能障碍的效果。这项前瞻性比较研究是针对因各种鼻腔疾病而出现嗅觉功能障碍并前来耳鼻喉科门诊就诊的患者进行的。在使用类固醇(A组)或生理盐水鼻喷雾剂(B组)之前和使用2周后,使用ODOFIN嗅觉棒对嗅觉进行定性评估,并记录和分析结果。总共选择了162名符合条件的患者。研究参与者大多数为男性,主要症状是嗅觉减退。在A组中,最初的嗅觉棒测试显示26例嗅觉丧失,55例嗅觉减退,2周后,分别只有2例和26例患者嗅觉丧失和嗅觉减退。而在B组中,即使经过2周治疗,嗅觉也没有明显改善。两组之间嗅觉改善情况有显著差异( = < 0.001)。我们使用ODOFIN嗅觉棒评估各种鼻腔疾病嗅觉功能障碍的研究表明,类固醇鼻喷雾剂是治疗嗅觉功能障碍的一种有效且安全的选择。