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[植物蜕皮甾体对正常肝脏及实验性肝炎胆汁分泌功能的作用]

[Action of phytoecdysteroids on the bile-secretory function of the normal liver and in experimental hepatitis].

作者信息

Syrov V N, Nabiev A N, Sultanov M B

出版信息

Farmakol Toksikol. 1986 May-Jun;49(3):100-3.

PMID:3720929
Abstract

Phytoecdysteroids from Rhaponticum carthemoides (Willd) Iljin and Ajuga turkestanica (Rgl.) Brig in a dose of 5 mg/kg per os markedly stimulate the bile secretion in normal rats treated with single (cyasterone) and 7-day-long (ecdysterone, cyasterone) administration. The chemical composition of the bile is significantly improved because of increased levels of bile acids and bilirubin and a decreased cholesterol content. Phytoecdysteroids (ecdysterone) exert more beneficial effect on the parameters under study in rats with toxic hepatitis induced by heliotrine.

摘要

来自新疆款冬(Willd)Iljin和突厥筋骨草(Rgl.)Brig的植物蜕皮甾类,以5毫克/千克的剂量口服,对单次给药(杯苋甾酮)和连续7天给药(蜕皮甾酮、杯苋甾酮)处理的正常大鼠的胆汁分泌有显著刺激作用。胆汁的化学成分因胆汁酸和胆红素水平升高以及胆固醇含量降低而得到显著改善。植物蜕皮甾类(蜕皮甾酮)对由天芥菜碱诱导的中毒性肝炎大鼠的研究参数有更有益的影响。

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