一种用于将蛋白质附着到脂质体膜上的新型疏水锚定物。
A new hydrophobic anchor for the attachment of proteins to liposomal membranes.
作者信息
Weissig V, Lasch J, Klibanov A L, Torchilin V P
出版信息
FEBS Lett. 1986 Jun 23;202(1):86-90. doi: 10.1016/0014-5793(86)80654-8.
PMID:3720949
Abstract
The model enzyme alpha-chymotrypsin covalently modified by a phosphatidylethanolamine derivative has been attached to liposomal membranes in high yield. A maximal protein/lipid ratio of 5.4 X 10(-3) mol enzyme/mol lipid was achieved.
摘要
经磷脂酰乙醇胺衍生物共价修饰的模型酶α-胰凝乳蛋白酶已以高产率附着于脂质体膜上。实现了5.4×10⁻³摩尔酶/摩尔脂质的最大蛋白质/脂质比。
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