Division of Nephrology, University of Washington, Seattle, WA; Division of Nephrology, Seattle Children's Hospital, Seattle, WA.
Fred Hutchinson Cancer Center, Seattle, WA.
Semin Nephrol. 2022 Nov;42(6):151348. doi: 10.1016/j.semnephrol.2023.151348. Epub 2023 May 18.
Transplant onconephrology is a growing specialty focused on the health care of kidney transplant recipients with cancer. Given the complexities associated with the care of transplant patients, along with the advent of novel cancer therapies such as immune checkpoint inhibitors and chimeric antigen-receptor T cells, there is a dire need for the subspecialty of transplant onconephrology. The management of cancer in the setting of kidney transplantation is best accomplished by a multidisciplinary team, including transplant nephrologists, oncologists, and patients. This review addresses the current state and future opportunities for transplant onconephrology, including the roles of the multidisciplinary team, and related scientific and clinical knowledge.
移植肿瘤肾脏病学是一个不断发展的专业领域,专注于癌症肾移植受者的医疗保健。考虑到移植患者护理的复杂性,以及免疫检查点抑制剂和嵌合抗原受体 T 细胞等新型癌症治疗方法的出现,移植肿瘤肾脏病学亚专业的需求非常迫切。多学科团队(包括移植肾脏病学家、肿瘤学家和患者)最适合管理肾移植患者中的癌症。这篇综述探讨了移植肿瘤肾脏病学的现状和未来机遇,包括多学科团队的作用以及相关的科学和临床知识。