Zweiban B, Cohen H, Chandrasoma P
Gastroenterology. 1986 Aug;91(2):469-74. doi: 10.1016/0016-5085(86)90585-8.
Three cases of Stevens-Johnson syndrome with intestinal involvement are described. Two patients had esophageal involvement, the severity of which paralleled skin lesions and, in 1 case, probably contributed to death. Dysphagia and bleeding were manifestations. The third patient was unique and had gastric, small and large bowel involvement with sparing of other mucosae. Cramps, severe exudative diarrhea, and bleeding were major clinical features. Unusual histologic features included sloughing of cells into the gland lumina of intestinal mucosa.
本文描述了3例伴有肠道受累的史蒂文斯-约翰逊综合征。2例患者有食管受累，其严重程度与皮肤病变平行，在1例患者中可能是导致死亡的原因。吞咽困难和出血是其表现。第3例患者较为特殊，有胃、小肠和大肠受累，其他黏膜未受累。痉挛、严重渗出性腹泻和出血是主要临床特征。不寻常的组织学特征包括肠黏膜腺腔内细胞脱落。
