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影像学检查在评估 30 岁以下女性乳腺癌中的表现及诊断价值。

The imaging findings and diagnostic value of radiology modalities to assess breast malignancy among women aged younger than 30 years.

机构信息

Department of Radiology, Shahid Beheshti University of Medical Sciences, Velenjak, Tehran Iran.

Department of Radiology, Yas Hospital and Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tohid Square, Tehran, Iran.

出版信息

Acta Radiol. 2023 Aug;64(8):2363-2370. doi: 10.1177/02841851231176271. Epub 2023 May 21.

Abstract

BACKGROUND

Breast cancer mainly affects women aged >50 years; however, younger women may also have advanced breast cancer, so early detection is important.

PURPOSE

To collect and review the imaging findings of women aged <30 years with breast cancer to find better diagnostic approaches for the early diagnosis of breast cancer in young women.

MATERIAL AND METHODS

In this study, 45 patients aged <30 years with a diagnosis of breast cancer were evaluated. Imaging assessments were performed based on ultrasound, mammography, and magnetic resonance imaging (MRI) findings. Finally, the findings were compared with the pathological results.

RESULTS

Predominant findings in ultrasound included irregular spiculated mass in 59.4%. In mammography, irregular high-density mass (46.5%) and suspicious micro calcification (42.8%) were the most common findings. In MRI, the predominant feature was a heterogeneous enhancing mass with an irregular shape and irregular margin (81%) with a 45% plateau and 36% washout kinetic pattern. In the pathology assessment, invasive ductal carcinoma was the most common finding (84.4%). All three modalities-MRI, ultrasonography, and mammography-are valuable, with sensitivities of 100%, 93.3%, and 90%, respectively.

CONCLUSION

Ultrasound, mammography, and MRI are highly sensitive and accurate tools for detecting breast cancer lesions in young women. Regular clinical breast examination with breast self-examination, and in suspected cases, ultrasound as the first imaging modality followed by mammography and/or MRI are the preferred diagnostic approach.

摘要

背景

乳腺癌主要影响 >50 岁的女性;然而,年轻女性也可能患有晚期乳腺癌,因此早期发现很重要。

目的

收集和回顾 <30 岁女性乳腺癌的影像学表现,以找到更好的诊断方法,实现年轻女性乳腺癌的早期诊断。

材料与方法

本研究共评估了 45 例 <30 岁诊断为乳腺癌的患者。根据超声、乳腺 X 线摄影和磁共振成像(MRI)的结果进行影像学评估。最后,将这些结果与病理结果进行比较。

结果

超声表现以形态不规则、有毛刺的团块为主(59.4%)。乳腺 X 线摄影中,不规则高密度肿块(46.5%)和可疑微钙化(42.8%)最常见。MRI 中,以形态不规则、边缘不规则的不均匀强化肿块为主(81%),具有 45%平台期和 36%流出型动力学特征。在病理评估中,最常见的发现是浸润性导管癌(84.4%)。MRI、超声和乳腺 X 线摄影这三种方法均具有较高的敏感性,分别为 100%、93.3%和 90%。

结论

超声、乳腺 X 线摄影和 MRI 是检测年轻女性乳腺癌病灶的高度敏感和准确工具。定期进行临床乳房检查和自我检查,在疑似病例中,首选超声作为初始影像学检查方法,然后进行乳腺 X 线摄影和/或 MRI。

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