Iacob Roxana, Iacob Emil Radu, Stoicescu Emil Robert, Ghenciu Delius Mario, Cocolea Daiana Marina, Constantinescu Amalia, Ghenciu Laura Andreea, Manolescu Diana Luminita
Department of Anatomy and Embriology, 'Victor Babeș' University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Doctoral School, 'Victor Babeș' University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Bioengineering (Basel). 2024 Mar 7;11(3):262. doi: 10.3390/bioengineering11030262.
Breast cancer, affecting both genders, but mostly females, exhibits shifting demographic patterns, with an increasing incidence in younger age groups. Early identification through mammography, clinical examinations, and breast self-exams enhances treatment efficacy, but challenges persist in low- and medium-income countries due to limited imaging resources. This review assesses the feasibility of employing breast ultrasound as the primary breast cancer screening method, particularly in resource-constrained regions. Following the PRISMA guidelines, this study examines 52 publications from the last five years. Breast ultrasound, distinct from mammography, offers advantages like radiation-free imaging, suitability for repeated screenings, and preference for younger populations. Real-time imaging and dense breast tissue evaluation enhance sensitivity, accessibility, and cost-effectiveness. However, limitations include reduced specificity, operator dependence, and challenges in detecting microcalcifications. Automatic breast ultrasound (ABUS) addresses some issues but faces constraints like potential inaccuracies and limited microcalcification detection. The analysis underscores the need for a comprehensive approach to breast cancer screening, emphasizing international collaboration and addressing limitations, especially in resource-constrained settings. Despite advancements, notably with ABUS, the primary goal is to contribute insights for optimizing breast cancer screening globally, improving outcomes, and mitigating the impact of this debilitating disease.
乳腺癌影响男女两性，但以女性为主，其人口统计学模式正在发生变化，年轻年龄组的发病率不断上升。通过乳房X线摄影、临床检查和乳房自我检查进行早期识别可提高治疗效果，但由于成像资源有限，中低收入国家仍面临挑战。本综述评估了采用乳腺超声作为主要乳腺癌筛查方法的可行性，特别是在资源有限的地区。遵循PRISMA指南，本研究审查了过去五年的52篇出版物。乳腺超声与乳房X线摄影不同，具有无辐射成像、适合重复筛查以及受年轻人群青睐等优点。实时成像和致密乳腺组织评估提高了敏感性、可及性和成本效益。然而，其局限性包括特异性降低、依赖操作者以及检测微钙化存在挑战。自动乳腺超声（ABUS）解决了一些问题，但面临潜在不准确和微钙化检测有限等限制。分析强调了乳腺癌筛查需要综合方法，强调国际合作并解决局限性，特别是在资源有限的环境中。尽管取得了进展，尤其是ABUS，但主要目标是为全球优化乳腺癌筛查、改善结果以及减轻这种使人衰弱疾病的影响提供见解。
