Institute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chinese Academy of Education Big Data, Qufu Normal University, Qufu, China.
Hum Vaccin Immunother. 2023 Dec 31;19(1):2211319. doi: 10.1080/21645515.2023.2211319. Epub 2023 May 22.
Vaccination can sufficiently ameliorate the coronavirus disease-2019 (COVID-19). Investigating what factors influence vaccine uptake may benefit ongoing vaccination efforts (e.g. booster injections, annual vaccination). The present study expanded Protection Motivation Theory with possible factors including perceived knowledge, adaptive responses, and maladaptive responses to develop a proposed model investigating vaccine uptake among United Kingdom (UK) and Taiwan (TW) populations. An online survey collected responses from UK ( = 751) and TW ( = 1052) participants (August to September, 2022). The results of structural equation modeling (SEM) showed that perceived knowledge was significantly associated with coping appraisal in both samples (standardized coefficient [β] = 0.941 and 0.898; < .001). Coping appraisal was correlated with vaccine uptake only in the TW sample (β = 0.319, < .05). Multigroup analysis showed there were significant differences between the path coefficients of perceived knowledge to coping and threat appraisals ( < .001), coping appraisal to adaptive and maladaptive responses ( < .001), as well as threat appraisal to adaptive response ( < .001). Such knowledge may improve vaccine uptake in Taiwan. The potential factors for the UK population require further investigation.
接种疫苗可以充分改善 2019 年冠状病毒病（COVID-19）。研究影响疫苗接种率的因素可能有助于正在进行的疫苗接种工作（例如加强针、年度接种）。本研究通过可能的因素扩展了保护动机理论，包括感知知识、适应性反应和对 COVID-19 的不适应反应，以开发一个针对英国（UK）和中国台湾（TW）人群的疫苗接种率的预测模型。一项在线调查于 2022 年 8 月至 9 月在英国（ = 751）和 TW（ = 1052）参与者中收集了数据。结构方程模型（SEM）的结果表明，感知知识与两个样本中的应对评估显著相关（标准化系数 [β] = 0.941 和 0.898； < .001）。只有在 TW 样本中，应对评估与疫苗接种率相关（β = 0.319， < .05）。多组分析显示，感知知识到应对和威胁评估的路径系数之间存在显著差异（ < .001），应对评估到适应性和不适应性反应的路径系数之间存在显著差异（ < .001），以及威胁评估到适应性反应的路径系数之间存在显著差异（ < .001）。这些知识可能会提高 TW 地区的疫苗接种率。英国人口的潜在因素需要进一步研究。
