Department of Pediatric Dentistry and Dental Public Health, Faculty of Dentistry, Alexandria University, Champolion, Alexandria, Egypt.
Department of Endodontics, Faculty of Dentistry, The Egyptian Russian University, Badr City, Egypt.
Sci Rep. 2024 Oct 1;14(1):22795. doi: 10.1038/s41598-024-72093-9.
Vaccines, like the Corona Virus Disease-2019 (COVID-19) vaccines, can control diseases, but vaccine hesitancy reduces their use. It is important to assess the intention to use COVID-19 vaccines boosters and the determinants of this intention to help in developing programs to promote the uptake of boosters. An online survey collected data from adults in Egypt between March and June 2022 using a questionnaire that assessed demographic characteristics, and constructs of the Theory of Planned Behaviour (TPB) and the Health Belief Model (HBM). The survey was uploaded to SurveyMonkey and the links were posted on social media platforms. Binary regression analysis was used and the dependent variable was intention to use boosters of COVID-19 vaccines. The independent variables were indicators of the HBM including perceived susceptibility to COVID-19 infection (medical history) and possibility of disease prevention (awareness of the availability of types of COVID-19 vaccines); and indicators of the TPB including attitude toward COVID-19 vaccines (that they are harmful, that they may lead to death and confidence in locally and foreign manufactured vaccines), perceived norms (the percentage of vaccinated persons in one's circle) and perceived control over booster uptake (presence of government mandates for COVID-19 vaccination). The confounders were sociodemographic factors (age, sex, education, and place of residence). Complete responses were available from 1113 out of 1401 participants (79.4%), with mean (SD) age = 25 (9.5) years, of whom, 66.7% (n = 742) were females and 68.6% (n = 764) were university students. About 39.4% and 31.2% indicated that they would get or would definitely get the booster dose of the COVID-19 vaccines. In multiple regression, intention to use a booster dose was significantly related to not agreeing (AOR = 4.87, P < 0.001) or not agreeing at all (AOR = 8.46, P = 0.001) that vaccines are harmful and to having no confidence (AOR = 0.21, P < 0.001) or no confidence at all (AOR = 0.14, P < 0.001) in foreign-manufactured vaccines. Most university-educated Egyptians in the study intended to take the COVID-19 vaccine booster dose and this intention was associated with attitude toward the harm of the vaccine and confidence in foreign-manufactured vaccines. Awareness campaigns are needed to counteract misinformation and promote booster dose uptake.
疫苗，如 2019 年冠状病毒病（COVID-19）疫苗，可以控制疾病，但疫苗犹豫会降低其使用。评估接种 COVID-19 疫苗加强针的意愿及其决定因素非常重要，这有助于制定促进加强针接种的方案。一项在线调查在 2022 年 3 月至 6 月期间从埃及成年人中收集数据，使用了一份评估人口统计学特征和计划行为理论（TPB）和健康信念模型（HBM）结构的问卷。该调查上传到 SurveyMonkey 上，并在社交媒体平台上发布链接。采用二元回归分析，因变量为使用 COVID-19 疫苗加强针的意愿。自变量是 HBM 的指标，包括对 COVID-19 感染的易感性（病史）和疾病预防的可能性（对 COVID-19 疫苗类型的认识）；以及 TPB 的指标，包括对 COVID-19 疫苗的态度（认为它们是有害的，可能导致死亡以及对国产和外国制造的疫苗的信心）、感知规范（自己圈子中接种疫苗的百分比）和对加强针接种的感知控制（是否有 COVID-19 疫苗接种的政府规定）。混杂因素是社会人口学因素（年龄、性别、教育和居住地）。在 1401 名参与者中，有 1113 名（79.4%）完成了完整的回复，平均（SD）年龄为 25（9.5）岁，其中 66.7%（n=742）为女性，68.6%（n=764）为大学生。约 39.4%和 31.2%表示他们将接种或肯定会接种 COVID-19 疫苗的加强针。在多元回归中，使用加强针的意愿与不同意（AOR=4.87，P<0.001）或完全不同意（AOR=8.46，P=0.001）疫苗有害以及对国产疫苗没有信心（AOR=0.21，P<0.001）或完全没有信心（AOR=0.14，P<0.001）显著相关。在研究中，大多数埃及大学生打算接种 COVID-19 疫苗加强针，这种意愿与对疫苗危害的态度和对外国制造疫苗的信心有关。需要开展宣传活动来消除错误信息，促进加强针的接种。
