School of Clinical Medicine, Fujian Medical University, Fuzhou, China.
Shengli Clinical Medical College of Fujian Medical University, Fuzhou, China.
Front Public Health. 2023 May 4;11:1080800. doi: 10.3389/fpubh.2023.1080800. eCollection 2023.
This study aimed to evaluate the awareness rate of prostate-specific antigen (PSA) among the general public in China and provide data about prostate cancer (PCa) for related scientific research.
A cross-sectional survey of PSA awareness was conducted in multiple regional populations using an online questionnaire. The questionnaire included basic information, knowledge about PCa, the awareness rate and application of PSA, and future expectations toward applying PSA screening in clinical practice. The study applied the methods of Pearson chi-square analysis and Logistic regression analysis.
A total of 493 valid questionnaires were included. Two hundred and nineteen respondents (44.4%) were males, and 274 (55.6%) were females. Of all respondents, 212 (43.0%) were under 20 years old, 147 (29.8%) were 20-30 years old, 74 (15.0%) were 30-40 years old, and 60 (12.2%) were over 40 years old. There are 310 people (62.9%) with medical educational background and 183 (37.1%) without. One hundred eighty-seven (37.9%) of the respondents were aware of PSA, and 306 (62.1%) were unaware of PSA. Statistically significant differences were obtained between the two groups regarding different ages, educational backgrounds, occupations, departments, and habits of knowing medical knowledge (all < 0.05). In addition, the differences between the group of aware of PSA (AP) and the group unaware of PSA (UAP) in terms of whether they had been exposed to PSA screening and whether they had exposure to PCa patients or related knowledge were also observed (all < 0.05). Age ≥30 years, medical educational background, understanding of medical knowledge, exposure to PCa patients or related knowledge, exposure to PSA screening, and status as a graduate student and above were independent factors for the occurrence of PSA awareness events (all < 0.05). In addition, age ≥ 30 years, medical educational background, and awareness of PSA were independent factors for future expectations toward PSA (all < 0.05).
We first analyzed the public awareness of PSA. Cognition degrees of PSA and PCa awareness vary among different populations in China. Therefore, we should designate corresponding widespread scientific educational programs for different populations to increase the awareness rate of PSA.
本研究旨在评估中国普通公众对前列腺特异性抗原（PSA）的认知率，并为前列腺癌（PCa）相关科学研究提供数据。
采用在线问卷对多个地区人群进行 PSA 认知横断面调查。问卷内容包括基本信息、PCa 相关知识、对 PSA 的认知率和应用情况，以及对 PSA 临床应用的未来期望。本研究采用 Pearson 卡方检验和 Logistic 回归分析方法。
共纳入 493 份有效问卷。219 名受访者（44.4%）为男性，274 名（55.6%）为女性。所有受访者中，212 名（43.0%）年龄在 20 岁以下，147 名（29.8%）年龄在 20-30 岁，74 名（15.0%）年龄在 30-40 岁，60 名（12.2%）年龄在 40 岁以上。有 310 名（62.9%）人具有医学教育背景，183 名（37.1%）人没有医学教育背景。187 名（37.9%）受访者知晓 PSA，306 名（62.1%）受访者不知晓 PSA。两组在年龄、教育背景、职业、科室和了解医学知识习惯等方面存在统计学差异（均<0.05）。此外，在是否接受过 PSA 筛查以及是否接触过 PCa 患者或相关知识方面，知晓 PSA（AP）组和不知晓 PSA（UAP）组之间也存在差异（均<0.05）。年龄≥30 岁、医学教育背景、了解医学知识、接触 PCa 患者或相关知识、接触 PSA 筛查以及研究生及以上学历是发生 PSA 知晓事件的独立因素（均<0.05）。此外，年龄≥30 岁、医学教育背景和 PSA 知晓是对 PSA 未来期望的独立因素（均<0.05）。
本研究首次分析了公众对 PSA 的认知情况。中国不同人群对 PSA 和 PCa 的认知程度存在差异。因此，我们应针对不同人群制定相应的广泛科学教育计划，以提高 PSA 的知晓率。
