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意大利心脏病学会(ANMCO)立场文件:关于在临床实践中对具有高突发性心脏性猝死风险的患者合理使用可穿戴式心脏复律除颤器的指南。

ANMCO position paper: guide to the appropriate use of the wearable cardioverter defibrillator in clinical practice for patients at high transient risk of sudden cardiac death.

作者信息

Casolo Giancarlo, Gulizia Michele Massimo, Aschieri Daniela, Chinaglia Alessandra, Corda Marco, Nassiacos Daniele, Caico Salvatore Ivan, Chimenti Cristina, Giaccardi Marzia, Gotti Enrico, Maffé Stefano, Magnano Roberta, Solarino Gianluca, Gabrielli Domenico, Oliva Fabrizio, Colivicchi Furio

机构信息

U.O.C. Cardiology, Versilia Hospital, Lido di Camaiore, Lucca 55043.

U.O.C. Cardiology, Garibaldi-Nesima Hospital, Azienda di Rilievo Nazionale e Alta Specializzazione 'Garibaldi', Catania.

出版信息

Eur Heart J Suppl. 2023 May 18;25(Suppl D):D294-D311. doi: 10.1093/eurheartjsupp/suad101. eCollection 2023 May.

Abstract

Extended risk stratification and optimal management of patients with a permanently increased risk of sudden cardiac death (SCD) are becoming increasingly important. There are several clinical conditions where the risk of arrhythmic death is present albeit only transient. As an example, patients with depressed left ventricular function have a high risk of SCD that may be only transient if there will be a significant recovery of function. It is important to protect the patients while receiving and titrating to the optimal dose the recommended drugs that may lead to an improved left ventricular function. In several other conditions, a transient risk of SCD can be observed even if the left ventricular function is not compromised. Examples are patients with acute myocarditis, during the diagnostic work-up of some arrhythmic conditions or after extraction of infected catheters while eradicating the associated infection. In all these conditions, it is important to offer a protection to these patients. The wearable cardioverter defibrillator (WCD) is of particular importance as a temporary non-invasive technology for both arrhythmia monitoring and therapy in patients with increased risk of SCD. Previous studies have shown the WCD to be an effective and safe therapy for the prevention of SCD caused by ventricular tachycardia/fibrillation. The aim of this ANMCO position paper is to provide a recommendation for clinical utilization of the WCD in Italy, based upon current data and international guidelines. In this document, we will review the WCD functionality, indications, clinical evidence, and guideline recommendations. Finally, a recommendation for the utilization of the WCD in routine clinical practice will be presented, in order to provide physicians with a practical guidance for SCD risk stratification in patients who may benefit from this device.

摘要

对心脏性猝死(SCD)风险持续增加的患者进行扩展风险分层和优化管理变得越来越重要。有几种临床情况,虽然心律失常死亡风险仅为短暂存在。例如,左心室功能减退的患者有较高的SCD风险,如果功能有显著恢复,这种风险可能只是短暂的。在接受并滴定至最佳剂量可能改善左心室功能的推荐药物时,保护患者很重要。在其他几种情况下,即使左心室功能未受损,也可观察到短暂的SCD风险。例如急性心肌炎患者、在某些心律失常情况的诊断检查期间或在拔除感染导管并消除相关感染后。在所有这些情况下,为这些患者提供保护很重要。可穿戴式心脏复律除颤器(WCD)作为一种临时非侵入性技术,对于SCD风险增加的患者进行心律失常监测和治疗尤为重要。先前的研究表明,WCD是预防室性心动过速/心室颤动所致SCD的一种有效且安全的治疗方法。本ANMCO立场文件的目的是根据当前数据和国际指南,为意大利WCD的临床应用提供建议。在本文件中,我们将回顾WCD的功能、适应证、临床证据和指南建议。最后,将提出WCD在常规临床实践中的应用建议,以便为医生在可能受益于该设备的患者中进行SCD风险分层提供实用指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e137/10194821/3949eaccca4a/suad101f1.jpg

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