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可穿戴式除颤器的应用范围超出现行指南:通过单一临床情况解释建立欧洲登记处的建议。

Expanded application of wearable cardioverter defibrillators beyond current guidelines: proposal for a European register explained through single clinical scenarios.

机构信息

Med1, Klinikum Fuerth, Fuerth, Bayern, Germany

Med1, Klinikum Fuerth, Fuerth, Bayern, Germany.

出版信息

Open Heart. 2024 Mar 8;11(1):e002597. doi: 10.1136/openhrt-2023-002597.

Abstract

The wearable cardioverter defibrillator (WCD) is becoming a more and more widely used instrument for the prevention of sudden cardiac death of patients either with a secondary prevention implantable cardioverter defibrillator indication or with a transient high risk of sudden cardiac death. Although clinical practice has demonstrated a benefit of protecting patients for a period as long as 3-6 months with such devices, the current European guidelines concerning ventricular arrhythmias and sudden cardiac death are still extremely restrictive in the patient selection in part because of the costs derived from such a prevention device, in part because of the lack of robust randomised trials.To illustrate expanded use cases for the WCD, four real-life clinical cases are presented where patients received the device slightly outside the established guidelines. These cases demonstrate the broader utility of WCDs in situations involving acute myocarditis, thyrotoxicosis, pre-excited atrial fibrillation and awaiting staging/prognosis of a lung tumour. The findings prompt expansion of the existing guidelines for WCD use to efficiently protect more patients whose risk of arrhythmic cardiac death is transient or uncertain. This could be achieved by establishing a European register of the patients who receive a WCD for further analysis.

摘要

可穿戴式心脏除颤器 (WCD) 正越来越广泛地用于预防具有继发性植入式心脏除颤器适应证或暂时存在高风险发生心源性猝死的患者发生心源性猝死。尽管临床实践已证实此类设备可保护患者长达 3-6 个月,但目前欧洲关于室性心律失常和心源性猝死的指南在患者选择方面仍极为受限,部分原因是源于预防设备的成本,部分原因是缺乏强有力的随机试验。为了说明 WCD 的扩展应用案例,呈现了四个实际临床案例,其中患者在稍超出既定指南的情况下接受了该设备。这些案例展示了 WCD 在急性心肌炎、甲状腺毒症、预激性心房颤动和等待肺部肿瘤分期/预后等情况下的更广泛用途。这些发现促使扩大 WCD 使用的现有指南,以更有效地保护那些心律失常性心源性猝死风险暂时或不确定的患者。这可以通过建立一个接受 WCD 的患者的欧洲登记册进行进一步分析来实现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6615/10928772/f4c8cabccc4b/openhrt-2023-002597f01.jpg

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