Upreti Prakash, Gongati Sudharsan R, Pandey Neelanjana, Saad Muhammad, Vittorio Timothy
Internal Medicine, Rochester Regional Health, Rochester, USA.
Internal Medicine, BronxCare Health System, Bronx, USA.
Cureus. 2023 Apr 16;15(4):e37660. doi: 10.7759/cureus.37660. eCollection 2023 Apr.
Venous thromboembolism (VTE) occurs due to venous stasis or low flow state within the blood vessels, resulting in subsequent fibrin and platelet aggregation leading to thrombosis. Arterial thrombosis affects various arteries including coronaries and is primarily due to platelet aggregation with little fibrin deposition leading to thrombosis. Although both arterial and venous thrombosis are considered as separate entities, some studies have suggested an association between them despite having distinctive causative factors. We retrospectively reviewed patients at our institution who were admitted with acute coronary syndrome (ACS) and underwent cardiac catheterization over a decade between 2009 and 2020 to look for patients who had both venous thromboembolic events and ACS. Here, we report a case series of three such patients who were found to have both VTE and coronary arterial thrombosis. However, it is unclear if having one of venous vs arterial clot increases the risk of having other vascular conditions, and further studies are needed to evaluate this hypothesis in the near future.
静脉血栓栓塞症（VTE）是由于血管内静脉淤滞或血流缓慢状态引起的，随后导致纤维蛋白和血小板聚集，进而形成血栓。动脉血栓形成会影响包括冠状动脉在内的各种动脉，主要是由于血小板聚集，几乎没有纤维蛋白沉积而导致血栓形成。尽管动脉血栓和静脉血栓被视为不同的实体，但一些研究表明，尽管它们有不同的致病因素，但两者之间存在关联。我们回顾性分析了2009年至2020年这十年间在我们机构因急性冠状动脉综合征（ACS）入院并接受心脏导管检查的患者，以寻找同时发生静脉血栓栓塞事件和ACS的患者。在此，我们报告了一个包含三名此类患者的病例系列，他们被发现同时患有VTE和冠状动脉血栓形成。然而，尚不清楚静脉或动脉血栓中的一种是否会增加患其他血管疾病的风险，在不久的将来还需要进一步的研究来评估这一假设。
