The Ohio State University College of Nursing, Columbus, Ohio, USA.
The Ohio State University, Columbus, Ohio, USA.
J Occup Health. 2023 Jan-Dec;65(1):e12404. doi: 10.1002/1348-9585.12404.
Prolonged and constant stress from work often leads to numerous adverse health effects. In recent years, interest in probiotics, living microorganisms that can benefit their host when consumed in adequate amounts, to aid health and well-being has increased. This scoping review is to systematically evaluate the current state of science on the effects of probiotic supplements on health, stress, and stress-related symptoms among working adults in occupational settings.
We performed a systematic scoping review following the Arksey and O'Malley Framework. Studies that examined the effects of probiotics on workers' health and stress-related indicators/outcomes in occupational settings were included. A comprehensive search was performed from November 2021 to January 2022 using MEDLINE/PubMed, Cochrane Library, CINAHL, PsychInfo, Scopus, and Embase.
A total of 14 papers met the inclusion and exclusion criteria. Probiotics consisted primarily of Lactobacillus and/or Bifidobacterium strains in various forms and doses. Three out of eight studies reported statistical differences in inflammatory markers or stress hormone levels between probiotic and placebo groups. Three of six reported reduced respiratory tract infection incidents in the probiotic groups and three out of four studies reported no differences in anxiety and depression between groups. Lastly, three studies found that absenteeism and presentism were lower in probiotic groups compared with placebo groups.
The potential benefits of probiotics exist; however, the measurements of outcomes, the types of probiotics used, and the characteristics of the intervention varied across studies. Further research is needed focusing on probiotics' direct and indirect mechanisms of action on the stress response and the standardization of strains and dosing.
工作中的长期持续压力常常导致许多不良健康影响。近年来，人们对益生菌的兴趣日益浓厚，益生菌是指当摄入足够量时可以使宿主受益的活菌，有助于促进健康和福祉。本范围综述旨在系统评估益生菌补充剂对职业环境中工作成年人健康、压力和与压力相关症状的影响的当前科学状态。
我们按照 Arksey 和 O'Malley 框架进行了系统的范围综述。纳入了研究益生菌对工人健康和与压力相关的指标/结果影响的研究。从 2021 年 11 月至 2022 年 1 月，我们使用 MEDLINE/PubMed、Cochrane 图书馆、CINAHL、PsychInfo、Scopus 和 Embase 进行了全面搜索。
共有 14 篇论文符合纳入和排除标准。益生菌主要由各种形式和剂量的乳杆菌和/或双歧杆菌菌株组成。八项研究中有三项报告了益生菌组和安慰剂组之间炎症标志物或应激激素水平的统计学差异。六项研究中有三项报告了益生菌组呼吸道感染事件减少，四项研究中有三项报告了两组之间焦虑和抑郁无差异。最后，三项研究发现益生菌组的旷工和缺勤率低于安慰剂组。
益生菌具有潜在的益处；然而，研究结果的测量、使用的益生菌类型以及干预的特征在研究之间存在差异。需要进一步研究益生菌对压力反应的直接和间接作用机制，并标准化菌株和剂量。
