Department of Pharmacology, Pediatrics and Organic Chemistry, Faculty of Pharmacy, Universidad Miguel Hernández de Elche, 03202 Elche, Spain.
MiBioPath Research Group, Health and Science Faculty, Catholic University of Murcia (UCAM), Campus de los Jerónimos n 135, 30107 Murcia, Spain.
Nutrients. 2021 Dec 10;13(12):4419. doi: 10.3390/nu13124419.
The occupational health impact of respiratory infectious diseases is costly to the economy and the health care system. Probiotics are non-pathogenic live microorganisms that, when ingested in adequate amounts, can colonize the intestinal tract, and enhance the immune system. In recent years, numerous studies have described the possible usefulness of certain probiotic strains in the treatment and prevention of respiratory tract infections, with disparate results. In order to assess the possible efficacy and safety of these microorganisms to prevent or ameliorate respiratory tract infections, we systematically searched the bibliographic databases MEDLINE (via Pubmed), EMBASE, The Cochrane library, Scopus, and Web of science, using the descriptors "Respiratory Tract Infections", "Probiotics", "Occupational Health", "Humans", and "Clinical Trials". After applying our inclusion and exclusion criteria, 18 studies were accepted for review and critical analysis. Our analysis suggests that a combination of different probiotics, most of them in the genus sp. and sp., could be a good mix to strengthen the immune system and reduce the symptoms of URTIs in the healthy working population.
呼吸道传染病对经济和医疗保健系统的职业健康影响代价高昂。益生菌是无毒的活体微生物，当摄入足够量时，它们可以在肠道中定植，并增强免疫系统。近年来，许多研究描述了某些益生菌菌株在治疗和预防呼吸道感染方面的可能用途，但结果却大相径庭。为了评估这些微生物预防或改善呼吸道感染的可能疗效和安全性，我们系统地检索了 MEDLINE（通过 Pubmed）、EMBASE、Cochrane 图书馆、Scopus 和 Web of science 等文献数据库，使用了“呼吸道感染”、“益生菌”、“职业健康”、“人类”和“临床试验”等描述词。在应用了我们的纳入和排除标准后，有 18 项研究被接受进行审查和批判性分析。我们的分析表明，不同益生菌的组合，其中大多数属于属 sp. 和 sp.，可能是一种很好的组合，可以增强免疫系统，并减轻健康工作人群中 URTIs 的症状。
