Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States.
Elmore Family School of Electrical and Computer Engineering, Purdue University, West Lafayette, Indiana 47907, United States.
Anal Chem. 2023 Jun 6;95(22):8411-8416. doi: 10.1021/acs.analchem.3c00735. Epub 2023 May 22.
Here, we have developed and applied a triple-barrel microelectrode. This device incorporates a platinum disk working electrode, a platinum disk counter electrode, and a low-leakage Ag/AgCl reference electrode into a small probe. We demonstrate that the incorporated low-leakage reference electrode shows similar voltammetry, potentiometry, and drift when compared to a commercial reference electrode in bulk solution. We also demonstrate the versatility of such a small three-channel system via voltammetry in nanoliter droplets and through electroanalysis of captured aerosols. Finally, we demonstrate the probe's potential utility in single-cell electroanalysis by making measurements within salmon eggs.
在这里，我们开发并应用了一种三管微电极。该装置将一个铂盘工作电极、一个铂盘对电极和一个低漏电流的 Ag/AgCl 参比电极集成到一个小探针中。我们证明，与在体溶液中的商业参比电极相比，所集成的低漏电流参比电极具有相似的伏安法、电位法和漂移性能。我们还通过纳升级液滴中的伏安法和捕获气溶胶的电化学分析展示了这种小型三通道系统的多功能性。最后，我们通过在鲑鱼卵内进行测量，证明了该探针在单细胞电化学分析中的潜在应用。
