Department of Pediatric Surgery, King Edward Medical University, Mayo Hospital, Lahore, Pakistan.
J Pak Med Assoc. 2023 May;73(5):1120-1122. doi: 10.47391/JPMA.6895.
Hepatic malignancies account for 1-4% of all childhood solid tumours and Hepatoblastoma is the most common malignant liver tumour in children. Its extrahepatic origin is rare. Here we present the case of a three-year-old boy who came with a large non-tender mass in the right upper abdomen for six months. Ultrasound abdomen revealed a huge heterogenous mass anterior to the right kidney and inferior to the liver with internal vascularity and calcifications, mimicking a neuroblastoma. Tru-cut needle biopsy showed foetal-type hepatoblastoma. After neoadjuvant chemotherapy, the tumour was explored. It was found to be adherent to the inferior surface of the liver with no capsular breech. Hence differentiating it from exophytic growth of hepatoblastoma. The tumour was completely resected. The postoperative course was uneventful and adjuvant chemotherapy was given. So far only a few cases of extrahepatic hepatoblastoma have been reported.
肝脏恶性肿瘤占儿童所有实体肿瘤的 1-4%，肝母细胞瘤是儿童最常见的肝脏恶性肿瘤。其肝外起源罕见。本文报告了一例 3 岁男孩，6 个月来因右上腹有一个大而无触痛的肿块就诊。腹部超声显示右肾前、肝脏下有一个巨大的混杂性肿块，内部有血管和钙化，类似于神经母细胞瘤。Tru-cut 针活检显示胎儿型肝母细胞瘤。新辅助化疗后，对肿瘤进行探查。发现肿瘤与肝脏下表面粘连，无包膜破裂，因此与肝母细胞瘤的外生性生长相鉴别。肿瘤被完全切除。术后过程顺利，并给予辅助化疗。到目前为止，仅报道了少数肝外肝母细胞瘤病例。
