Matsuo Yuya, Ichikawa Yoshitoshi, Sawada Genta, Takada Akihiro, Kim Ho-Min, Murakami Masahiro, Fukunaga Hiroki, Shirai Setsuko, Kondou Satoko, Kimura Hayato, Morita Shunji
Dept. of Surgery, Itami City Hospital.
Gan To Kagaku Ryoho. 2023 May;50(5):647-649.
A 62-year-old man with anal pain was diagnosed with rectal neuroendocrine carcinoma. There were multiple metastases in the liver, lung, paraaortic lymph node, and bone of the patient. After performing a diverting colostomy, irinotecan and cisplatin were administered. Partial response was obtained after 2 courses, and anal pain improved. However, after 8 courses, multiple skin metastases were found on his back. At the same time, the patient also complained of redness, pain, and impaired vision in the right eye. Iris metastasis was diagnosed clinically by ophthalmologic examination and with contrast- enhanced MRI. Iris metastasis was treated with 5 doses of 4 Gy irradiation, ameliorating the eye symptoms. The patient died of the original disease 13 months after the initial diagnosis; however, multidisciplinary treatment appeared effective for palliating cancer symptoms.
一名62岁的男性因肛门疼痛被诊断为直肠神经内分泌癌。该患者的肝脏、肺、主动脉旁淋巴结和骨骼均有多处转移。在进行转流性结肠造口术后，给予伊立替康和顺铂治疗。2个疗程后获得部分缓解，肛门疼痛有所改善。然而，8个疗程后，其背部发现多处皮肤转移。同时，患者还抱怨右眼发红、疼痛和视力受损。通过眼科检查和增强磁共振成像在临床上诊断为虹膜转移。对虹膜转移进行了5次剂量为4 Gy的放疗，眼部症状得到改善。患者在初次诊断后13个月死于原发病；然而，多学科治疗似乎对缓解癌症症状有效。
