阿拉利亚努达苷A，一种来自……的具有抗气道炎症活性的不寻常骨架三萜皂苷。 （注：原文“Aralianudaside A”可能有误，推测正确名称是“Aralia nudicaulis saponin A”，即东北土当归皂苷A ，翻译内容根据推测名称给出的一个合理翻译供你参考，具体以实际为准。）
Aralianudaside A, an unusual skeleton triterpenoid saponin with anti-airway inflammatory activity from .
作者信息
Yin Pengcheng, Qian Haishan, Li Shaohua, Tang Benqin, Wang Juan, Chen Shuai, Ni Guanghui, Dong Fawu, Li Yanping, Huang Feng, Zhang Rongping, He Hongping, Li Baojing
机构信息
Yunnan Key Laboratory of Southern Medicinal Utilization, College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming, China.
Department of Medical Science, Shunde Polytechnic, Foshan, China.
出版信息
Nat Prod Res. 2024 Mar;38(6):1036-1043. doi: 10.1080/14786419.2023.2214290. Epub 2023 May 23.
Aralianudaside A, a triterpene saponin with an unusual skeleton of pentacyclic triterpenoid, along with a new triterpene glycoside and six known compounds were obtained from the buds of . Their structures were determined through extensive spectral analysis, including HRESIMS, IR, 1D and 2D NMR, glycolysis and GC. All compounds were evaluated for anti-airway inflammatory activity in lipopolysaccharides (LPS)-induced airway epithelial cells (16HBE), compounds , , , and significantly decreased the expression of pro-inflammatory cytokines IL-1β and IL-4.
阿拉柳苷A是一种具有不寻常五环三萜骨架的三萜皂苷，从……的芽中获得了一种新的三萜糖苷和六种已知化合物。通过广泛的光谱分析确定了它们的结构，包括高分辨电喷雾电离质谱、红外光谱、一维和二维核磁共振光谱、糖酵解和气相色谱。在脂多糖（LPS）诱导的气道上皮细胞（16HBE）中对所有化合物进行了抗气道炎症活性评估，化合物……、……、……、……和……显著降低了促炎细胞因子IL-1β和IL-4的表达。 （注：原文中部分化合物名称未给出具体内容，用省略号代替）
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