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2011-2021 年巴西 COVID-19 大流行前后早产儿的患病率和时间趋势:一项历史性时间序列分析。

Prevalence and temporal trend of prematurity in Brazil before and during the COVID-19 pandemic: a historical time series analysis, 2011-2021.

机构信息

Universidade do Sul de Santa Catarina, Curso de Medicina, Tubarão, SC, Brazil.

Universidade do Sul de Santa Catarina, Programa de Pós-Graduação em Ciências da Saúde, Palhoça, SC, Brazil.

出版信息

Epidemiol Serv Saude. 2023 May 19;32(2):e2022603. doi: 10.1590/S2237-96222023000200005. eCollection 2023.

Abstract

OBJECTIVE

to measure the prevalence of prematurity according to the Brazilian macro-regions and maternal characteristics over the past 11 years; to compare the proportions during the COVID-19 pandemic (2020-2021) with those of the historical series (2011-2019).

METHODS

this was an ecological study, with data from the Live Birth Information System; the prevalence was calculated according to year, macro-region and maternal characteristics; time series analysis was performed using Prais-Winsten regression model.

RESULTS

the prevalence of preterm birth in 2011-2021 was 11.1%, stable; the average in the pandemic period 11.3% (95%CI 11.2;11.4%) was similar to that of the base period 11.0% (95%CI 10.6;11.5%); the North region (11.6%) showed the highest proportion between 2011 and 2021; twin pregnancy (56.3%) and pregnant women who had 4-6 prenatal care visits (16.7%) showed an increasing trend (p-value < 0.001); the highest prevalence was observed for extremes of maternal age, pregnant women of Black race/skin color, indigenous women and those with lower level of education.

CONCLUSION

preterm birth rates were highest for socially vulnerable pregnant women, twin pregnancies and in the North; stable prevalence, with no difference between periods.

摘要

目的

根据巴西的宏观区域和产妇特征,测量过去 11 年来早产的流行率;将 COVID-19 大流行期间(2020-2021 年)的比例与历史系列(2011-2019 年)进行比较。

方法

这是一项生态学研究,使用来自活产信息系统的数据;根据年份、宏观区域和产妇特征计算流行率;使用 Prais-Winsten 回归模型进行时间序列分析。

结果

2011-2021 年早产的流行率为 11.1%,稳定;大流行期间的平均流行率为 11.3%(95%CI 11.2;11.4%)与基础期 11.0%(95%CI 10.6;11.5%)相似;2011-2021 年间,北部地区(11.6%)的比例最高;双胞胎妊娠(56.3%)和接受 4-6 次产前检查的孕妇(16.7%)呈上升趋势(p 值<0.001);母亲年龄极端、黑皮肤/黑人、土著妇女和受教育程度较低的孕妇的早产率最高。

结论

社会弱势群体、双胞胎妊娠和北部地区的早产率最高;流行率稳定,两个时期之间没有差异。

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