Department of Surgery, Division of Surgical Oncology, City of Hope Comprehensive Cancer Center, Duarte, California, USA.
Department of Surgery, Division of Colorectal Surgery, City of Hope Comprehensive Cancer Center, Duarte, California, USA.
J Surg Oncol. 2023 Jun;127(8):1247-1251. doi: 10.1002/jso.27320.
The incidence of colorectal cancer in young adults (CRCYAs) is increasing globally, and it is now the third leading cause of cancer death among young adults under 50 years old. The rising incidence is attributed to various emerging risk factors such as genetics, lifestyle factors, and microbiome profiles. Delayed diagnosis and more advanced disease presentation contribute to worse outcomes. A multidisciplinary approach to care is crucial to ensure comprehensive and personalized treatment plans for CRCYA.
全球范围内，年轻人（CRCYA）结直肠癌的发病率正在上升，目前该病已成为 50 岁以下年轻人癌症死亡的第三大原因。发病率上升归因于遗传、生活方式因素和微生物组特征等各种新兴风险因素。诊断延迟和更晚期的疾病表现导致预后更差。多学科治疗方法至关重要，可确保为 CRCYA 制定全面和个性化的治疗计划。
