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骨科与创伤外科中基于证据的医学与基于专业知识的医学:没有什么比一个好理论更实用了。

[Evidence-based versus expertise-based medicine in orthopedic and trauma surgery : There is nothing more practical than a good theory].

作者信息

Stengel Dirk, Wünscher Johannes, Dubs Luzi, Ekkernkamp Axel, Renkawitz Tobias

机构信息

BG Kliniken - Klinikverbund der gesetzlichen Unfallversicherung gGmbH, Leipziger Platz 1, 10117, Berlin, Deutschland.

, Winterthur, Schweiz.

出版信息

Orthopadie (Heidelb). 2023 Jun;52(6):435-446. doi: 10.1007/s00132-023-04382-6. Epub 2023 May 24.

DOI:10.1007/s00132-023-04382-6
PMID:37222750
Abstract

About a quarter of a century after the introduction of the concept and principles of evidence-based medicine (EbM), some healthcare providers are still adamant that these are incompatible with knowledge gained through experience. Across the surgical disciplines, it is often argued EbM underestimates or neglects the importance of intuition and surgical skills. To put it bluntly, these assumptions are wrong and often characterized by a misunderstanding of the methodology of EbM. Even the best controlled trial cannot be properly interpreted or implemented without clinical reasoning; furthermore, clinicians of all disciplines are obligated to provide care according to the current state of scientific knowledge. In an era of revolutionary biomedical developments, exponential increase of research but incremental innovations, they must become familiar with pragmatic tools to appraise the validity and relevance of clinical study results, and to decide whether there is a need to adapt current beliefs and practices based on the new information. We herein use the recent example of a new medical device for the surgical treatment of rotator cuff tears and subacromial impingement syndrome to illustrate how important it is to interpret data in the context of a precise, answerable question and to combine clinical expertise with methodological principles offered by EbM.

摘要

在循证医学(EbM)的概念和原则引入大约四分之一个世纪后,一些医疗服务提供者仍然坚信这些与通过经验获得的知识不相容。在各个外科领域,人们常常认为循证医学低估或忽视了直觉和手术技能的重要性。直白地说,这些假设是错误的,并且常常表现出对循证医学方法的误解。即使是最好的对照试验,如果没有临床推理也无法得到恰当的解释或实施;此外,所有学科的临床医生都有义务根据科学知识的现状提供医疗服务。在生物医学发生革命性发展、研究呈指数级增长但创新却逐步递增的时代,他们必须熟悉实用工具,以评估临床研究结果的有效性和相关性,并决定是否需要根据新信息调整当前的信念和实践。我们在此以一种用于治疗肩袖撕裂和肩峰下撞击综合征的新型医疗设备为例,来说明在精确、可回答的问题背景下解读数据以及将临床专业知识与循证医学提供的方法原则相结合是多么重要。

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The development of network meta-analysis.网络荟萃分析的发展。
J R Soc Med. 2022 Aug;115(8):313-321. doi: 10.1177/01410768221113196.
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InSpace Implant Compared with Partial Repair for the Treatment of Full-Thickness Massive Rotator Cuff Tears: A Multicenter, Single-Blinded, Randomized Controlled Trial.《全层巨大肩袖撕裂的内置物修补与部分修复治疗的比较:一项多中心、单盲、随机对照试验》。
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A systematic review of the effect of early mobilisation on length of stay for adults in the intensive care unit.一项系统评价早期活动对 ICU 成人住院时间影响的研究。
Nurs Crit Care. 2023 Jul;28(4):499-509. doi: 10.1111/nicc.12785. Epub 2022 Jun 1.
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Effects of non-pharmacological interventions for preventing delirium in general ward inpatients: A systematic review & meta-analysis of randomized controlled trials.非药物干预对预防普通病房住院患者谵妄的效果:一项随机对照试验的系统评价与荟萃分析。
PLoS One. 2022 May 6;17(5):e0268024. doi: 10.1371/journal.pone.0268024. eCollection 2022.
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Subacromial balloon spacer for irreparable rotator cuff tears of the shoulder (START:REACTS): a group-sequential, double-blind, multicentre randomised controlled trial.肩袖不可修复撕裂的肩峰下球囊扩张间隔器(START:REACTS):一项群组序贯、双盲、多中心随机对照试验。
Lancet. 2022 May 21;399(10339):1954-1963. doi: 10.1016/S0140-6736(22)00652-3. Epub 2022 Apr 21.
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Machine Learning for the Orthopaedic Surgeon: Uses and Limitations.骨科医生的机器学习:用途与局限
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Artificial intelligence in orthopedic surgery: evolution, current state and future directions.骨科手术中的人工智能:发展历程、现状与未来方向。
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