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皮质醇和扶他林对大鼠实验性布氏锥虫感染中贫血和体温变化的比较作用。

The comparative effects of cortisol and voltaren on anaemia and temperature changes in experimental Trypanosoma brucei infection in rats.

作者信息

Shoyinka S V, Uzoukwu M

出版信息

J Comp Pathol. 1986 May;96(3):277-84. doi: 10.1016/0021-9975(86)90047-2.

Abstract

Three groups of rats were infected with Trypanosoma brucei. Two of the groups were treated with either asteroidal (Cortisol) or a non-steroidal (Voltaren) anti-inflammatory drug to compare the effects of the two drugs on the disease process. The anaemia was least severe in the Cortisol treated group which suggests that its supportive use in the treatment of natural infections with the brucei subgroup of trypanosomes may be advantageous.

摘要

三组大鼠感染了布氏锥虫。其中两组分别用甾体类抗炎药(皮质醇)或非甾体类抗炎药(扶他林)进行治疗,以比较这两种药物对疾病进程的影响。皮质醇治疗组的贫血症状最轻,这表明在治疗锥虫属布氏锥虫亚群的自然感染时辅助使用皮质醇可能有益。

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